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Lung Cancer clinical trials in San Diego, CA

23 studies for Lung Cancer are looking for participants at sites in and around San Diego (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Kaiser Permanente-San Diego Zion, San Diego
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • University of California San Diego Moores Cancer Center, San Diego
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, San Diego
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

RecruitingPhase 2
  • UC San Diego Medical Center - Bankers Hill, San Diego
  • UC San Diego McGrath Outpatient Pavilion - Hillcrest, San Diego
  • UC San Diego Medical Center- Hillcrest, San Diego
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07476287

A Registry for People With Lung Cancer

RecruitingObservational study
  • University of California San Diego (Data collection), San Diego
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06424327

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • University Of California - San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

RecruitingPhase 1/2
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06287775

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Scripps Health, San Diego
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • University of California, San Diego (UCSD) - Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

RecruitingPhase 1
  • University of California - San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06343402

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • UC San Diego Medical Center - Hillcrest, San Diego
  • California Protons Cancer Therapy Center, San Diego
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • University of California, San Diego Moores Cancer Center, San Diego
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • UCSD Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Kaiser Permanente-San Diego Zion, San Diego
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • University of California San Diego (UC San Diego) Health - Jacobs Medical Center - Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer

RecruitingPhase 1/2
  • VA San Diego Healthcare System, San Diego, CA, San Diego
Ages 18 and older · All sexes · Updated Jan 27, 2026 · NCT05467748

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, La Jolla · 11 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • UCSD Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Next Generation Chest X-Ray Tomosynthesis for Screening of Lung Cancer

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Diego, San Diego
Ages 30 to 85 · All sexes · Updated Aug 29, 2024 · NCT06577883

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in San Diego

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.