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Lung Cancer clinical trials in Florida
79 studies for Lung Cancer are looking for participants at sites in Florida.
Cities in Florida
- Tampa31 studies
- Orlando23 studies
- Miami22 studies
- Jacksonville18 studies
- Deltona9 studies
- Gainesville9 studies
- Hollywood9 studies
- Fort Lauderdale8 studies
- Sarasota8 studies
- Plantation6 studies
- St. Petersburg6 studies
- Pembroke Pines5 studies
- Coral Springs5 studies
- Largo4 studies
- Lakeland4 studies
- Clearwater4 studies
- Cape Coral4 studies
- Kendall3 studies
- Miami Beach3 studies
- Deerfield Beach3 studies
- Palm Bay3 studies
- West Palm Beach3 studies
- Spring Hill3 studies
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Boca Raton Clinical Research Coral Springs, Coral Springs
- Regis Clinical Research LLC, Miami
- Florida Clinical Trials Group Tamarac, Tamarac
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Nov 13, 2026 · NCT05920356A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
- Helios Clinical Research - Fort Lauderdale, Fort Lauderdale
- Mayo Clinic in Florida, Jacksonville
- Local Institution - 0523, Tampa
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07063745Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-based Chemotherapy With or Without Amivantamab for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
- Local Institution - 0142, Pembroke Pines
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07100080This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
- Mid Florida Hematology and Oncology Center, Orange City
- BRCR Global, Plantation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06758401Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
- Morton Plant Hospital, Clearwater
- Miami Cancer Institute, Miami
- South Florida Baptist Hospital, Plant City
- and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06498635BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)
- Total Health and Research Center, Miami
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07625644Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
- Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
- Holy Cross Hospital, Fort Lauderdale
- Regional Cancer Center-Lee Memorial Health System, Fort Myers
- and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04267848Evaluate the Clinical Performance of the Flow Cytometry - FlowPath Lung Test as a Sensitive and Specific Non-invasive Diagnostic of Sputum Samples to Identify/Detect the Presence of Lung Cancer in High-risk Individuals Who Have Existing Lung Nodules, 6 to <30 mm in Diameter, Determined by LDCT.
- Bay Pines VA Healthcare System, Bay Pines
- Miami VA Healthcare System, Miami
- James A. Haley Veterans' Hospital, Tampa
Recruiting
Ages 50 to 80 · All sexes · Updated Nov 12, 2026 · NCT07168993Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
- UM Sylvester Comprehensive Cancer Center at Aventura, Aventura
- UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
- and 13 more
RecruitingPhase 3
Ages 70 and older · All sexes · Updated Nov 12, 2026 · NCT06096844A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation
- Florida Cancer Specialists, Sarasota
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07458347A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
- Mayo Clinic in Florida ( Site 0014), Jacksonville
- Mount Sinai Cancer Center ( Site 0038), Miami Beach
- Mid Florida Hematology and Oncology Center ( Site 0018), Orange City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06312137A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]
- GSK Investigational Site, Hialeah
- GSK Investigational Site, Miami
- GSK Investigational Site, Plantation
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07099898Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
- Clermont Oncology Center, Clermont
- Mid Florida Hematology and Oncology Center, Orange City
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT04198766Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer
- University of Miami, Coral Gables
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06791057A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials
- University of Florida, Gainesville
- Mayo Clinic in Florida, Jacksonville
- University of Miami, Miami
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Nov 5, 2026 · NCT05655494A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
- Florida Cancer Specialists - SOUTH - SCRI - PPDS, Fort Myers
- University of Florida Health at Shands, Gainesville
- BioResearch Partner, Hialeah
- and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06793215Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib as First Line Treatment in Metastatic Non-squamous RAS G12D-Mutated NSCLC
- Helios CR, Inc. - The Oncology Institute of Hope and Innovation - Fort Lauderdale, Fort Lauderdale
- Florida Clinical Trials Group, LLC, Plantation
- Florida Clinical Trials Group, Plantation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07777822Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
- Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
- Morton Plant Hospital, Clearwater
- and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
- Holy Cross Hospital, Fort Lauderdale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT04181060VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
- Holy Cross Hospital (site 213), Fort Lauderdale
- Memorial Cancer Institute at Memorial Healthcare Systems (site 132), Pembroke Pines
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT03556228SI-B036-ST-101 in Advanced/Metastatic Solid Tumors
- Florida Cancer Specialists Lake Nona, Orlando
- Florida Cancer Specialists Sarasota, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07857616A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- Millennium Oncology Research Clinic, Hollywood
- Miami Cancer Institute at Baptist Health, Inc., Miami
- Ocala Oncology Center PL DBA Florida Cancer Affiliates - Ocala, Ocala
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06119581Safety and Efficacy of OBX-115 in Advanced Solid Tumors
- University of Miami, Miami
- Advent Health Orlando, Orlando
- Orlando Health Cancer Institute (Melanoma/NSCLC), Orlando
- and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06060613Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)
- Clermont Oncology Center, Clermont
- SSAK Partners, LLC., Coral Springs
- Baptist Medical Center Jacksonville, Jacksonville
- and 4 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT06712316Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
- Orlando Health Cancer Center, Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07499674Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer
- Mayo Clinic in Florida, Jacksonville
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT05746325Cemiplimab and Fianlimab Before Surgery for the Treatment of Stage IB-IIIB Non-Small Cell Lung Cancer
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06918132Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer
- UF Health Cancer Institute - Gainesville, Gainesville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06287775A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
- Research Site, Orlando
- Research Site, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06835569A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
- AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06172478BRain-AVOidant Proton Craniospinal Irradiation for Leptomeningeal Metastases From Solid Tumor Malignancies
- University of Miami, Miami
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07789912Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy
- Miami VA Healthcare System, Miami, FL, Miami
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT02984761Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
- Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT06922591A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
- Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT07154290Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
- Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT06810544Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
- Boca Raton Clinical Research Associates, Plantation
- H Lee Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT06162221AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
- Avenzo Therapeutics Recruiting Site, Orlando
- Avenzo Therapeutics Recruiting Site, Sarasota
- Avenzo Therapeutics Recruiting Site, Tampa
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Oct 16, 2026 · NCT07038343Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
- Cancer Care Centers of Brevard, Inc, Palm Bay
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06712355Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
- University of Miami, Miami
- Sarah Cannon Research Institute - Lake Nona Florida, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06293898A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
- D&H Cancer Research Center - Margate, Margate
- Alpha Oncology Research, Orange City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07128199From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.