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Lung Cancer clinical trials in Florida
76 studies for Lung Cancer are looking for participants at sites in Florida.
Cities in Florida
- Tampa29 studies
- Orlando21 studies
- Miami20 studies
- Jacksonville17 studies
- Hollywood9 studies
- Gainesville9 studies
- Deltona8 studies
- St. Petersburg7 studies
- Plantation7 studies
- Fort Lauderdale7 studies
- Sarasota7 studies
- Cape Coral5 studies
- Pembroke Pines5 studies
- Largo5 studies
- West Palm Beach4 studies
- Clearwater4 studies
- Lakeland4 studies
- Palm Coast3 studies
- Palm Bay3 studies
- Miami Beach3 studies
- Port Saint Lucie3 studies
- Deerfield Beach3 studies
- Coral Springs3 studies
- Spring Hill3 studies
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
- Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
- Holy Cross Hospital, Fort Lauderdale
- Regional Cancer Center-Lee Memorial Health System, Fort Myers
- and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT04267848Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
- Florida Cancer Specialists & Research Institute - South, Fort Myers
- BRCR Global, Plantation
- Cancer Care Centers of Breevard, Rockledge
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
- Holy Cross Hospital, Fort Lauderdale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT04181060Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
- Morton Plant Hospital, Clearwater
- Miami Cancer Institute, Miami
- South Florida Baptist Hospital, Plant City
- and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06498635A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)
- Clermont Oncology Center ( Site 0041), Clermont
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07286149A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
- AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
- Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07154290Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
- Florida Cancer Specialists, Bonita Springs
- Florida Cancer Specialists, Bradenton
- Florida Cancer Specialists, Cape Coral
- and 46 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
- Mayo Clinic in Florida ( Site 0014), Jacksonville
- Mount Sinai Cancer Center ( Site 0038), Miami Beach
- Mid Florida Hematology and Oncology Center ( Site 0018), Orange City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312137A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Boca Raton Clinical Research Coral Springs, Coral Springs
- Florida Clinical Trials Group Plantation, Plantation
- Florida Clinical Trials Group Tamarac, Tamarac
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
- Mid Florida Hematology and Oncology Center, Orange City
- BRCR Global, Plantation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
- UM Sylvester Comprehensive Cancer Center at Aventura, Aventura
- UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
- and 13 more
RecruitingPhase 3
Ages 70 and older · All sexes · Updated Sep 24, 2026 · NCT06096844A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
- University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
- Helios Clinical Research - Fort Lauderdale, Fort Lauderdale
- Mayo Clinic in Florida, Jacksonville
- Local Institution - 0523, Tampa
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07063745Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
- Clermont Oncology Center, Clermont
- SSAK Partners, LLC., Coral Springs
- Baptist Medical Center Jacksonville, Jacksonville
- and 4 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- Florida Cancer Specialists, Sarasota
- Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
- Local Institution - 0142, Pembroke Pines
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07100080A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
- Florida Cancer Specialists & Research Institute - Sarasota, Sarasota
- Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer
- UF Health Cancer Institute - Gainesville, Gainesville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06287775BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)
- Total Health and Research Center, Miami
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07625644Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05681780The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- University of Miami - Sylvester Comprehensive Cancer Center, Miami
- Advent Health, Orlando
- Florida Cancer Specialists South, Port Charlotte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
- University of Miami, Miami
- Sarah Cannon Research Institute - Lake Nona Florida, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06625775A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- Millennium Oncology Research Clinic, Hollywood
- University of Florida - Jacksonville, Jacksonville
- Miami Cancer Institute at Baptist Health, Inc., Miami
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
- Florida Cancer Specialists - SOUTH - SCRI - PPDS, Fort Myers
- University of Florida Health at Shands, Gainesville
- BioResearch Partner, Hialeah
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06793215A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
- University of Miami, Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
- Avenzo Therapeutics Recruiting Site, Orlando
- Avenzo Therapeutics Recruiting Site, Sarasota
- Avenzo Therapeutics Recruiting Site, Tampa
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation
- Moffitt Cancer Center-International Plaza, Tampa
- Moffitt Cancer Center - McKinley Campus, Tampa
- Moffitt Cancer Center, Tampa
- and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07012031Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
- Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
- Morton Plant Hospital, Clearwater
- and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
- Cancer Care Centers of Brevard, Inc, Palm Bay
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06712355Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
- Sylvester Comprehensive Cancer Center Miami, Miami
- AdventHealth Cancer Institute, Orlando
- H Lee Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06765109Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1/2
Ages 16 and older · All sexes · Updated Aug 20, 2026 · NCT05269381Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib as First Line Treatment in Metastatic Non-squamous RAS G12D-Mutated NSCLC
- Florida Clinical Trials Group, LLC, Plantation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07777822Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
- Orlando Health Cancer Center, Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07499674Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
- UM Sylvester Comprehensive Cancer Center at Aventura, Aventura
- UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
- Bay Pines VA Healthcare System, Bay Pines
- Morton Plant Hospital, Clearwater
- Halifax Health Cancer Center for Hope - Daytona Beach, Daytona Beach
- and 7 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
- AdventHealth Celebration, Celebration
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma
- Xencor Investigative Site, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07285044From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.