Home › Lung Cancer › South Carolina
Lung Cancer clinical trials in South Carolina
19 studies for Lung Cancer are looking for participants at sites in South Carolina.
Cities in South Carolina
- Charleston11 studies
- Greenville9 studies
- Greer7 studies
- Spartanburg7 studies
- Anderson5 studies
- Columbia4 studies
- Florence4 studies
- Easley3 studies
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- Prisma Health Cancer Institute - Spartanburg, Boiling Springs
- Bon Secours Saint Francis Hospital, Charleston
- and 15 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT04267848Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
- Ralph H Johnson VA Medical Center, Charleston
- Medical University of South Carolina, Charleston
RecruitingPhase 3
Ages 70 and older · All sexes · Updated Sep 30, 2026 · NCT06096844Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
- Prisma Health Cancer Institute - Spartanburg, Boiling Springs
- Prisma Health Cancer Institute - Easley, Easley
- Gibbs Cancer Center-Gaffney, Gaffney
- and 9 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06498635A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Medical University of South Carolina, Florence
- Medical University of South Carolina Health Lancaster Medical Center, Lancaster
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
- Saint Joseph's Candler Health System ( Site 4010), Bluffton
- Medical University of South Carolina-Hollings Cancer Center ( Site 0045), Charleston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312137A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
- Local Institution - 0608, Greenville
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07063745A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- Medical University of South Carolina, Charleston
- Prisma Health Cancer Institute, Greenville
- Lexington Medical Center, West Columbia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- AnMed Health Cancer Center, Anderson
- Prisma Health Richland Hospital, Columbia
- McLeod Regional Medical Center, Florence
- and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069Health Education Approach to Lung Screening
- Medical University of South Carolina, Charleston
RecruitingHealthy volunteers welcome
Ages 50 to 80 · All sexes · Updated Aug 25, 2026 · NCT06070870Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- Gibbs Cancer Center-Gaffney, Gaffney
- Saint Francis Hospital, Greenville
- and 8 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996Prediction Augmented Screening Initiative
- Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Recruiting
Ages 50 to 80 · All sexes · Updated Jun 26, 2026 · NCT06538636Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
- AnMed Health Cancer Center, Anderson
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- Prisma Health Cancer Institute - Spartanburg, Boiling Springs
- and 9 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
- AnMed Health Cancer Center, Anderson
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- Medical University of South Carolina, Charleston
- and 5 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
- AnMed Health Cancer Center, Anderson
RecruitingPhase 2
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- Medical University of South Carolina, Charleston
- McLeod Health, Florence
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
- AnMed Health Cancer Center, Anderson
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- Gibbs Cancer Center-Gaffney, Gaffney
- and 7 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Greenville
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening
- Medical University of South Carolina (MUSC), Charleston
- McLeod Health, Florence
RecruitingObservational study
Ages 50 and older · All sexes · Updated Aug 5, 2025 · NCT06122077Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
- Ralph H. Johnson VA Health Care System, Charleston
RecruitingObservational study
Ages 29 to 85 · All sexes · Updated Nov 13, 2024 · NCT06426628From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.