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Lung Cancer clinical trials in Texas
101 studies for Lung Cancer are looking for participants at sites in Texas.
Cities in Texas
- Houston78 studies
- Dallas27 studies
- San Antonio26 studies
- Austin8 studies
- The Woodlands7 studies
- Irving6 studies
- Sugar Land6 studies
- League City6 studies
- Amarillo5 studies
- El Paso4 studies
- Tyler4 studies
- Fort Worth3 studies
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
- Hendrick Medical Center, Abilene
- Houston Methodist San Jacinto Hospital, Baytown
- Parkland Memorial Hospital, Dallas
- and 6 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT04267848Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
- Parkland Memorial Hospital, Dallas
- UT Southwestern/Simmons Cancer Center-Dallas, Dallas
- UT Southwestern Clinical Center at Richardson/Plano, Richardson
RecruitingPhase 3
Ages 70 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT06096844Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
- Houston Methodist San Jacinto Hospital, Baytown
- Houston Methodist Cypress Hospital, Cypress
- UT Southwestern/Simmons Cancer Center-Dallas, Dallas
- and 6 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT04181060A Study of PHN-012 in Patients With Advanced Solid Tumors
- PHN-012-001 Site, Houston
- PHN-012-001 Site, San Antonio
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT07127874Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
- Texas Oncology - South Austin, Austin
- Texas Oncology Dallas, Dallas
- MD Anderson Cancer Center, Houston
- and 1 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT06881784Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)
- Texas Oncology - DFW ( Site 8003), Dallas
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT06780098Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
- Texas Oncology - West Texas, Abilene
- Texas Oncology - Northeast Texas, Allen
- Texas Oncology - West Texas, Amarillo
- and 52 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07222566This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
- The University of Texas, MD Anderson Cancer Center - Woodlands, Conroe
- Renovatio Clinical - El Paso, El Paso
- The University of Texas MD Anderson Cancer Center Diagnostic Imaging, Houston
- and 10 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT06758401A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
- University of Texas Medical Branch, Galveston
- The University of Texas MD Anderson Cancer Center, Houston
- Baylor Scott & White Health, Temple
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07154290A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Oncology Consultants PA, Houston
- University of Texas MD Anderson Cancer Center, Houston
- US Oncology Research Investigational Products Center, Irving
RecruitingPhase 3
Ages 18 to 100 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT05920356A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
- The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT06172478A Registry for People With Lung Cancer
- Baylor University Medical Center (Data Collection Only), Dallas
- MD Anderson Cancer Center (Data Collection Only), Houston
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06424327Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer
- Research Site, Houston
RecruitingPhase 2
Ages 18 to 95 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT05061550A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
- NEXT Oncology - Irving, Irving
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 23, 2026 ยท NCT06618287A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
- Local Institution - 0433, Dallas
- University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 2/3
Ages 18 and older ยท All sexes ยท Updated Sep 23, 2026 ยท NCT07063745Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- MD Anderson, Houston
- NEXT Dallas, Irving
- NEXT Oncology San Antonio, San Antonio
- and 1 more
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT06128551Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
- Local Institution - 0025, Houston
- Local Institution - 0173, San Antonio
RecruitingPhase 2/3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07100080A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
- The University of Texas MD Anderson Cancer Center - Texas Medical Center, Houston
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 21, 2026 ยท NCT07629960Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
- M D Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 18, 2026 ยท NCT04038619Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
- NEXT - Dallas, Dallas
- NEXT, San Antonio
- START - San Antonio, San Antonio
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 17, 2026 ยท NCT07349537Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
- MD Anderson Cancer Center, Houston
- START San Antonio, San Antonio
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT05786924Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation
- M D Anderson Cancer Center, Houston
Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT05010109The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- New Experimental Therapeutics - NEXT Oncology, Austin
- Texas Oncology, Bedford
- UT Southwest Simmons Cancer Center, Dallas
- and 2 more
RecruitingPhase 1/2
Ages 12 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT04585750The Rise in Robotic Atypical Segmentectomies
- M D Anderson Cancer Center, Houston
RecruitingObservational study
All ages ยท All sexes ยท Updated Sep 14, 2026 ยท NCT04644952Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
- Start - Dfw, Fort Worth
- Oncology Consultants, Houston
- START - San Antonio, San Antonio
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 10, 2026 ยท NCT06293898Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
- SCRI at Mary Crowley, Dallas
- University of Texas Southwestern Medical Center, Dallas
- The University of Texas MD Anderson Cancer Center, Houston
- and 1 more
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 9, 2026 ยท NCT06625775A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
- The University of Texas Southwestern Medical Center at Dallas, Dallas
- Renovatio Clinical - El Paso, El Paso
- JPS Health Network, Fort Worth
- and 5 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT06793215A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- USO - Texas Oncology, Austin
- William Beaumont Army Medical Center, Fort Bliss
- Houston Methodist Hospital, Houston
- and 3 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT06119581A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
- MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT06561685A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
- The University of Texas - MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 4, 2026 ยท NCT06400472AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
- Avenzo Therapeutics Recruiting Site, Dallas
- Avenzo Therapeutics Recruiting Site, Houston
- Avenzo Therapeutics Recruiting Site, San Antonio
RecruitingPhase 1/2
Ages 18 to 75 ยท All sexes ยท Updated Sep 4, 2026 ยท NCT07038343Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer
- Oncology Consultants Texas Medical Center, Houston
- USOR - Texas Oncology - (DFW) Waco, Waco
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 3, 2026 ยท NCT06343402Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy
- M D Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 3, 2026 ยท NCT04892953Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- The Don and Sybil Harrington Cancer Center, Amarillo
- UT MD Anderson Cancer Center, Houston
- Audie L Murphy VA Hospital, San Antonio
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 ยท All sexes ยท Updated Sep 2, 2026 ยท NCT05334069Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations
- Texas Oncology, Dallas
- The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 1, 2026 ยท NCT07185997Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
- The University of Texas MD Anderson Cancer Center, Houston
- Texas Oncology Cancer Center, Sugar Land
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 1, 2026 ยท NCT06712355Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
- START San Antonio, San Antonio
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Aug 27, 2026 ยท NCT06582017Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigating Radiation-response and Toxicity
- The University of Texas M. D. Anderson Cancer Center, Houston
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Aug 25, 2026 ยท NCT06909201Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
- University of Texas, MD Anderson Cancer Center, Houston
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 19, 2026 ยท NCT07499674Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
- MD Anderson in The Woodlands, Conroe
- Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
- Ben Taub General Hospital, Houston
- and 4 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 17, 2026 ยท NCT05624996From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.