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Lung Cancer clinical trials in San Antonio, TX

26 studies for Lung Cancer are looking for participants at sites in and around San Antonio (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, San Antonio
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • NEXT Oncology San Antonio, San Antonio
  • START Texas, San Antonio
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

RecruitingPhase 2/3
  • Local Institution - 0173, San Antonio
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07100080

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • NEXT, San Antonio
  • START - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • New Experimental Therapeutics of San Antonio - NEXT Oncology, San Antonio
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • START - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • University of Texas San Antonio (UTSA), San Antonio
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06625775

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, San Antonio
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Audie L Murphy VA Hospital, San Antonio
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • UT Health Mays Cancer Center, San Antonio
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics, San Antonio
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07444814

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

RecruitingPhase 1/2
  • Mays Cancer Center / University of Texas, San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT05652686

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site #2, San Antonio
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • START, San Antonio
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT07223047

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Next Oncology, San Antonio
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A Study of ZW251 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT07164313

Patient-derived Organoid Model and Circulating Tumor Cells for Treatment Response of Lung Cancer

RecruitingObservational study
  • UT Health San Antonio, M.D. Anderson Cancer Center, San Antonio
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT03655015

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • South Texas Accelerated Research Therapeutics, LLC, San Antonio
  • UT Health San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

RecruitingPhase 1/2
  • Next Oncology, San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jan 29, 2026 · NCT07148128

Collection of Sputum and Labeling for Lung Cancer

RecruitingObservational studyHealthy volunteers welcome
  • South Texas Veterans Health Care System (STVHCS)/Audie L. Murphy Memorial Veterans Hospital, San Antonio
Ages 21 and older · All sexes · Updated Apr 1, 2025 · NCT03457415

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in San Antonio

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.