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Lung Diseases clinical trials recruiting in the U.S.

56 studies for Lung Diseases are recruiting participants at sites across the United States.

Lung diseases are disorders or infections that affect the lungs and cause breathing problems. Some can lead to respiratory failure. Find out more about prevention, living with lung diseases, and treatment.

Cities with the most studies

By state

Recently updated studies

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT01730092

Role of Genetic Factors in the Development of Lung Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 90 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT00001532

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT06977581

Study of the Disease Process of Lymphangioleiomyomatosis

RecruitingObservational study
Ages 16 to 100 ยท All sexes ยท Updated Nov 5, 2026 ยท NCT00001465

A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

RecruitingPhase 2
Ages 40 to 75 ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07759245

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

RecruitingPhase 3
28 Days ยท All sexes ยท Updated Nov 4, 2026 ยท NCT02735707

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 30, 2026 ยท NCT05624450

Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD

Recruiting
Ages 40 to 90 ยท All sexes ยท Updated Oct 27, 2026 ยท NCT05572632

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT02984761

Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)

RecruitingPhase 3
Ages 40 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT07284602

BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma

RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT05341726

Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT01776398

Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma

RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 21, 2026 ยท NCT07120503

Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for Pulmonary Diseases

RecruitingPhase 1
All ages ยท All sexes ยท Updated Oct 16, 2026 ยท NCT05147688

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 14, 2026 ยท NCT07013474

Study of Lung Proteins in Patients With Pneumonia

RecruitingObservational study
Ages 3 to 99 ยท All sexes ยท Updated Oct 13, 2026 ยท NCT00077909

Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 8, 2026 ยท NCT07489066

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT06765109

A Study of COVID-19 Vaccine(s) in Children and Adults

RecruitingPhase 3Healthy volunteers welcome
Ages 5 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07798648

American Lung Association (ALA) Lung Health Cohort

RecruitingObservational studyHealthy volunteers welcome
Ages 25 to 35 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT04543461

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.