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Lung Diseases clinical trials recruiting in the U.S.
57 studies for Lung Diseases are recruiting participants at sites across the United States.
Lung diseases are disorders or infections that affect the lungs and cause breathing problems. Some can lead to respiratory failure. Find out more about prevention, living with lung diseases, and treatment.
Cities with the most studies
- Houston, TX15 studies
- Boston, MA14 studies
- Durham, NC13 studies
- New York City, NY12 studies
- Miami, FL10 studies
- Dallas, TX10 studies
- Washington, DC10 studies
- Ann Arbor, MI10 studies
- Pittsburgh, PA10 studies
- Nashville, TN10 studies
- Los Angeles, CA10 studies
- Columbus, OH10 studies
- Birmingham, AL9 studies
- Chicago, IL9 studies
- Philadelphia, PA8 studies
- Orlando, FL8 studies
- Baltimore, MD8 studies
- Charleston, SC7 studies
- Seattle, WA7 studies
- Jacksonville, FL7 studies
- Atlanta, GA7 studies
- Cincinnati, OH7 studies
- Detroit, MI7 studies
- Tampa, FL7 studies
- Kansas City, KS6 studies
- Salt Lake City, UT6 studies
- St. Louis, MO6 studies
- Portland, OR5 studies
- Indianapolis, IN5 studies
- Arlington, VA5 studies
- Hialeah, FL5 studies
- San Francisco, CA5 studies
- Louisville, KY5 studies
- Winston-Salem, NC5 studies
- Oklahoma City, OK5 studies
- Cleveland, OH4 studies
- Richmond, VA4 studies
- Minneapolis, MN4 studies
- Tucson, AZ4 studies
- Kansas City, MO4 studies
By state
- Alabama13 studies
- Arizona9 studies
- California30 studies
- Colorado12 studies
- District of Columbia6 studies
- Florida26 studies
- Georgia11 studies
- Hawaii3 studies
- Idaho3 studies
- Illinois16 studies
- Indiana5 studies
- Kansas9 studies
- Kentucky9 studies
- Louisiana5 studies
- Maryland13 studies
- Massachusetts15 studies
- Michigan17 studies
- Minnesota7 studies
- Missouri8 studies
- Nebraska4 studies
- Nevada6 studies
- New Jersey6 studies
- New Mexico3 studies
- New York16 studies
- North Carolina18 studies
- Ohio18 studies
- Oklahoma5 studies
- Oregon5 studies
- Pennsylvania20 studies
- Rhode Island3 studies
- South Carolina11 studies
- Tennessee15 studies
- Texas22 studies
- Utah7 studies
- Vermont4 studies
- Virginia10 studies
- Washington8 studies
- Wisconsin3 studies
Recently updated studies
A Study of COVID-19 Vaccine(s) in Children and Adults
RecruitingPhase 3Healthy volunteers welcome
Ages 5 and older · All sexes · Updated Sep 28, 2026 · NCT07798648Study of the Disease Process of Lymphangioleiomyomatosis
RecruitingObservational study
Ages 16 to 100 · All sexes · Updated Sep 28, 2026 · NCT00001465Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT01730092A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07013474Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07489066A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
RecruitingPhase 2
Ages 40 to 75 · All sexes · Updated Sep 25, 2026 · NCT07759245A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 25, 2026 · NCT06679140American Lung Association (ALA) Lung Health Cohort
RecruitingObservational studyHealthy volunteers welcome
Ages 25 to 35 · All sexes · Updated Sep 23, 2026 · NCT04543461Study of Lung Proteins in Patients With Pneumonia
RecruitingObservational study
Ages 3 to 99 · All sexes · Updated Sep 22, 2026 · NCT00077909A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Sep 22, 2026 · NCT06977581Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07407933Role of Genetic Factors in the Development of Lung Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 90 · All sexes · Updated Sep 10, 2026 · NCT00001532A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06572384Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
RecruitingPhase 2
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07059091Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 3, 2026 · NCT07284602A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT05967689Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05624450A Phase 1 Trial of AMG 691 in Healthy Chinese and Japanese Volunteers
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 60 · All sexes · Updated Aug 27, 2026 · NCT07745907A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma
RecruitingPhase 2
Ages 4 to 11 · All sexes · Updated Aug 27, 2026 · NCT07525375Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06765109Understanding New Cachexia Subtypes Through Observational Epidemiological Research
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07776353A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Aug 11, 2026 · NCT07555483From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.