Home โบ Lung Diseases
Lung Diseases clinical trials recruiting in the U.S.
56 studies for Lung Diseases are recruiting participants at sites across the United States.
Lung diseases are disorders or infections that affect the lungs and cause breathing problems. Some can lead to respiratory failure. Find out more about prevention, living with lung diseases, and treatment.
Cities with the most studies
- Houston, TX16 studies
- Boston, MA14 studies
- Durham, NC13 studies
- New York City, NY13 studies
- Pittsburgh, PA11 studies
- Dallas, TX10 studies
- Los Angeles, CA10 studies
- Ann Arbor, MI10 studies
- Miami, FL10 studies
- Columbus, OH10 studies
- Chicago, IL9 studies
- Washington, DC9 studies
- Orlando, FL9 studies
- Philadelphia, PA8 studies
- Birmingham, AL8 studies
- Nashville, TN8 studies
- Baltimore, MD7 studies
- Detroit, MI7 studies
- Charleston, SC7 studies
- Cincinnati, OH7 studies
- Seattle, WA7 studies
- Tampa, FL7 studies
- Hialeah, FL6 studies
- Atlanta, GA6 studies
- Salt Lake City, UT6 studies
- St. Louis, MO6 studies
- Kansas City, KS6 studies
- Jacksonville, FL6 studies
- San Francisco, CA5 studies
- Winston-Salem, NC5 studies
- Oklahoma City, OK5 studies
- Indianapolis, IN5 studies
- Arlington, VA5 studies
- Louisville, KY5 studies
- Portland, OR5 studies
- Cleveland, OH4 studies
- Orange, CA4 studies
- Denver, CO4 studies
- Burlington, VT4 studies
- Providence, RI4 studies
By state
- Alabama12 studies
- Arizona9 studies
- California30 studies
- Colorado12 studies
- District of Columbia5 studies
- Florida29 studies
- Georgia10 studies
- Hawaii3 studies
- Idaho3 studies
- Illinois16 studies
- Indiana5 studies
- Kansas9 studies
- Kentucky9 studies
- Louisiana5 studies
- Maryland12 studies
- Massachusetts15 studies
- Michigan17 studies
- Minnesota6 studies
- Missouri8 studies
- Nebraska4 studies
- Nevada5 studies
- New Jersey6 studies
- New Mexico3 studies
- New York17 studies
- North Carolina19 studies
- Ohio19 studies
- Oklahoma5 studies
- Oregon5 studies
- Pennsylvania21 studies
- Rhode Island4 studies
- South Carolina11 studies
- Tennessee13 studies
- Texas23 studies
- Utah7 studies
- Vermont4 studies
- Virginia10 studies
- Washington8 studies
- Wisconsin3 studies
Recently updated studies
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT01730092Role of Genetic Factors in the Development of Lung Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 90 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT00001532A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT06977581Study of the Disease Process of Lymphangioleiomyomatosis
RecruitingObservational study
Ages 16 to 100 ยท All sexes ยท Updated Nov 5, 2026 ยท NCT00001465A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
RecruitingPhase 2
Ages 40 to 75 ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07759245Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
RecruitingPhase 3
28 Days ยท All sexes ยท Updated Nov 4, 2026 ยท NCT02735707A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06119581Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 30, 2026 ยท NCT05624450Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD
Recruiting
Ages 40 to 90 ยท All sexes ยท Updated Oct 27, 2026 ยท NCT05572632A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)
RecruitingPhase 3
Ages 18 to 80 ยท All sexes ยท Updated Oct 26, 2026 ยท NCT07555483Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy
Recruiting
Ages 18 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT02984761Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)
RecruitingPhase 3
Ages 40 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT07284602BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT05341726Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 23, 2026 ยท NCT01776398Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 21, 2026 ยท NCT07120503Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for Pulmonary Diseases
RecruitingPhase 1
All ages ยท All sexes ยท Updated Oct 16, 2026 ยท NCT05147688A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
RecruitingPhase 3
Ages 12 and older ยท All sexes ยท Updated Oct 15, 2026 ยท NCT06679140A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 14, 2026 ยท NCT07013474A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma
RecruitingPhase 2
Ages 4 to 11 ยท All sexes ยท Updated Oct 13, 2026 ยท NCT07525375Study of Lung Proteins in Patients With Pneumonia
RecruitingObservational study
Ages 3 to 99 ยท All sexes ยท Updated Oct 13, 2026 ยท NCT00077909Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 8, 2026 ยท NCT07489066A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 6, 2026 ยท NCT05967689Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT06765109A Study of COVID-19 Vaccine(s) in Children and Adults
RecruitingPhase 3Healthy volunteers welcome
Ages 5 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07798648American Lung Association (ALA) Lung Health Cohort
RecruitingObservational studyHealthy volunteers welcome
Ages 25 to 35 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT04543461From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.