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Macular Degeneration clinical trials recruiting in the U.S.
55 studies for Macular Degeneration are recruiting participants at sites across the United States.
Macular degeneration, or age-related macular degeneration (AMD), causes vision loss in older adults. Learn about the types and what can help.
Cities with the most studies
- Dallas, TX13 studies
- Erie, PA10 studies
- The Woodlands, TX9 studies
- Hagerstown, MD8 studies
- Sacramento, CA8 studies
- Reno, NV8 studies
- Austin, TX7 studies
- Carmel, IN7 studies
- Houston, TX7 studies
- Fort Worth, TX7 studies
- Salt Lake City, UT7 studies
- Santa Monica, CA7 studies
- Boston, MA7 studies
- Phoenix, AZ7 studies
- Cleveland, OH7 studies
- Washington, DC6 studies
- Cincinnati, OH6 studies
- Portland, OR6 studies
- Nashville, TN6 studies
- Naperville, IL6 studies
- Raleigh, NC6 studies
- Mountain View, CA6 studies
- Columbia, SC6 studies
- Philadelphia, PA6 studies
- McAllen, TX6 studies
- Fort Lauderdale, FL5 studies
- Lynchburg, VA5 studies
- Orlando, FL5 studies
- Syracuse, NY5 studies
- Spokane, WA5 studies
- Tampa, FL5 studies
- San Antonio, TX5 studies
- Eugene, OR5 studies
- San Francisco, CA5 studies
- Pensacola, FL5 studies
- Durham, NC5 studies
- Jacksonville, FL4 studies
- St. Petersburg, FL4 studies
- Memphis, TN4 studies
- Cicero, IL4 studies
By state
- Arizona11 studies
- California20 studies
- Colorado7 studies
- Connecticut6 studies
- Florida14 studies
- Georgia6 studies
- Illinois13 studies
- Indiana7 studies
- Maryland11 studies
- Massachusetts14 studies
- Michigan9 studies
- Minnesota5 studies
- Mississippi5 studies
- Missouri5 studies
- Nevada8 studies
- New Jersey7 studies
- New York10 studies
- North Carolina11 studies
- Ohio11 studies
- Oklahoma3 studies
- Oregon9 studies
- Pennsylvania17 studies
- South Carolina8 studies
- Tennessee7 studies
- Texas24 studies
- Utah9 studies
- Virginia7 studies
- Washington8 studies
- Wisconsin6 studies
Recently updated studies
National Eye Institute Biorepository for Retinal Diseases
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 120 · All sexes · Updated Sep 28, 2026 · NCT01496625A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
RecruitingPhase 1/2
Ages 55 and older · All sexes · Updated Sep 23, 2026 · NCT07029945Cell Collection to Study Eye Diseases
RecruitingObservational studyHealthy volunteers welcome
1 Day – 120 Years · All sexes · Updated Sep 22, 2026 · NCT01432847A Study in Adults With Geographic Atrophy
RecruitingPhase 2
Ages 60 and older · All sexes · Updated Sep 21, 2026 · NCT07606365A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
RecruitingPhase 2/3
Ages 50 and older · All sexes · Updated Sep 18, 2026 · NCT07440225A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
RecruitingPhase 3
Ages 50 to 85 · All sexes · Updated Sep 18, 2026 · NCT06541704The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06319872A Study About the Safety of a Single ASP2020 Eye Injection and if it Helps People With Vision Loss From Stargardt-type Eye Conditions
RecruitingPhase 1
Ages 6 and older · All sexes · Updated Sep 16, 2026 · NCT07734064A Phase 2 Study of NT-101 Topical in Patients With Wet AMD
RecruitingPhase 2
Ages 50 and older · All sexes · Updated Sep 16, 2026 · NCT07811726A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
RecruitingPhase 2/3
Ages 60 and older · All sexes · Updated Sep 14, 2026 · NCT06635148Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
RecruitingPhase 2
Ages 55 and older · All sexes · Updated Sep 10, 2026 · NCT06659445A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
RecruitingPhase 1
Ages 50 and older · All sexes · Updated Sep 3, 2026 · NCT03178149A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)
RecruitingObservational study
Ages 55 and older · All sexes · Updated Sep 3, 2026 · NCT07144137Noninvasive Imaging Biomarkers of Treatable Macrovascular Disease in Age-related Macular Degeneration.
RecruitingObservational study
Ages 50 to 80 · All sexes · Updated Sep 3, 2026 · NCT07798323A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD
RecruitingObservational study
Ages 50 and older · All sexes · Updated Sep 1, 2026 · NCT06346600Effect of Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation on Skin Carotenoid Concentration: A Six-Month, Placebo-Controlled Crossover Study
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06965426SGLT2 Inhibitors in Geographic Atrophy
RecruitingPhase 2
Ages 50 and older · All sexes · Updated Aug 26, 2026 · NCT07174687Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration
Recruiting
Ages 60 and older · All sexes · Updated Aug 26, 2026 · NCT06662162A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults
RecruitingObservational study
Ages 6 and older · All sexes · Updated Aug 25, 2026 · NCT074255744D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
RecruitingPhase 1/2
Ages 50 and older · All sexes · Updated Aug 21, 2026 · NCT05197270A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD
RecruitingPhase 2
Ages 55 and older · All sexes · Updated Aug 20, 2026 · NCT06659549Phase 1 Study of C.001 in Retinal Degeneration
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07594236AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance
RecruitingHealthy volunteers welcome
Ages 50 to 89 · All sexes · Updated Aug 10, 2026 · NCT06619405A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
RecruitingPhase 2/3
Ages 50 and older · All sexes · Updated Aug 6, 2026 · NCT07496567Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants
RecruitingPhase 1
Ages 50 and older · All sexes · Updated Aug 5, 2026 · NCT07230834From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.