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Major Depressive Disorder clinical trials in Tennessee

6 studies for Major Depressive Disorder are looking for participants at sites in Tennessee.

Cities in Tennessee

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

  • Clinical Neuroscience Solutions Inc. - Memphis, Mephis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

  • Clinical Neuroscience Solutions, Inc., Memphis
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

  • Psychiatric Consultants, PC, Franklin
RecruitingPhase 2
Ages 18 to 64 · All sexes · Updated Jul 27, 2026 · NCT07115329

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

  • Clinical Research Site, Memphis
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Jul 24, 2026 · NCT07484217

A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

  • Clinical Neuroscience Solutions /ID# 278192, Memphis
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Jun 15, 2026 · NCT07276997

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

  • Clinical Research Site, Memphis
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.