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Melanoma clinical trials in Virginia
34 studies for Melanoma are looking for participants at sites in Virginia.
Cities in Virginia
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
- Inova Schar Cancer Infusion Pharmacy, Fairfax
- Inova Schar Cancer, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07519655A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)
- Inova Schar Cancer Institute ( Site 4046), Fairfax
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06961006A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
- University of Virginia, Charlottesville
- Inova Schar Cancer Institute, Fairfax
- Virginia Commonwealth University Massey Cancer Center, Richmond
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
- Inova Alexandria Hospital, Alexandria
- Inova Schar Cancer Institute, Fairfax
- Inova Fair Oaks Hospital, Fairfax
- and 6 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196Pan-tumor MRD Study
- Virginia Cancer Institute, Richmond
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma
- University of Virginia Cancer Center, Charlottesville
- VCU Massey Cancer Center at Stony Point, Richmond
- VCU Massey Comprehensive Cancer Center, Richmond
RecruitingPhase 3
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074A Study of BI 3810944 in Patients With Advanced Cancer
- University of Virginia Health System, Charlottesville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07224425Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
- Virginia Cancer Specialists-Fairfax, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07287917Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Chesapeake Regional Medical Center, Chesapeake
- Augusta Health Center for Cancer and Blood Disorders, Fishersville
- Bon Secours Memorial Regional Medical Center, Mechanicsville
- and 7 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
- Virginia Cancer Specialists, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285Project: Every Child for Younger Patients With Cancer
- University of Virginia Cancer Center, Charlottesville
- Inova Fairfax Hospital, Falls Church
- Children's Hospital of The King's Daughters, Norfolk
- and 3 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
- Research Site, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
- Virginia Commonwealth University, Richmond
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06425926A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors
- Clinical Trial Site, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07749586A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
- Virginia Cancer Specialists, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors
- NEXT Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06270706DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
- USA05-0, Virginia Beach
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
- Next Oncology Virginia, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985Neoadjuvant Darovasertib in Primary Uveal Melanoma
- Augusta Health, Center for Cancer and Blood Disorders, Fishersville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
- NEXT Oncology - Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06326411Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
- Augusta Health Center for Cancer and Blood Disorders, Fishersville
- Hematology Oncology Associates of Fredericksburg Inc, Fredericksburg
- Centra Alan B Pearson Regional Cancer Center, Lynchburg
- and 5 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors
- NEXT Virginia, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07317505Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients
- VCU - McGlothlin Medical Education Center, Richmond
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT03567889Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC
- NEXT Oncology, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 24, 2025 · NCT06332755A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
- Research Site 102, Fairfax
- Research Site 112, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma
- University of Virginia, Charlottesville
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Nov 20, 2025 · NCT06472661SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Charlottesville
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
- Virginia Cancer Specialists, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT04370587Excision of Lymph Node Trial (EXCILYNT) (Mel69)
- Cancer Center at the University of Virginia, Charlottesville
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2025 · NCT05839912A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
- Virginia Cancer Specialists, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 13, 2025 · NCT05669430A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
- NEXT Virginia, Fairfax
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jan 7, 2025 · NCT06090266Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
- University of Virginia Health System, Charlottesville
- VCU Massey Cancer Center Peninsula Cancer Institute, Newport News
- VCU Massey Cancer Center, Richmond
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors
- Massey Cancer Center, Richmond
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 18, 2024 · NCT05280314A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors
- Next Oncology, Virginia Cancer Specialists, Fairfax
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 26, 2024 · NCT05746897From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.