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Mental Fatigue clinical trials recruiting in the U.S.

12 studies for Mental Fatigue are recruiting participants at sites across the United States.

By state

Recently updated studies

ME/CFS Brain Fog: Cognitive Rehabilitation Trial

Recruiting
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07523113

Effects of Caffeine on Chess Performance and Cognitive Function in Professional Chess Players

RecruitingHealthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Sep 30, 2026 · NCT07641335

Acute Mental Fatigue and Muscle Strength

RecruitingHealthy volunteers welcome
Ages 18 to 39 · All sexes · Updated Sep 29, 2026 · NCT07846618

CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · Women · Updated Jul 1, 2026 · NCT07679074

Water-based Activity to Enhance Recovery in Long COVID-19

Recruiting
Ages 18 to 89 · All sexes · Updated Jun 18, 2026 · NCT06142253

Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog

Recruiting
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT06614309

Transcranial Direct Current Stimulation for Post Treatment Lyme Disease

Recruiting
Ages 18 to 70 · All sexes · Updated May 6, 2026 · NCT06915324

The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors

Recruiting
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT06938555

Effects of Hemp-Derived Cannabinoids on Menopause Symptoms

RecruitingPhase 2Healthy volunteers welcome
Ages 40 to 60 · Women · Updated Mar 10, 2026 · NCT07393672

A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications

RecruitingHealthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Feb 2, 2026 · NCT07380412

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Jan 22, 2026 · NCT04806620

Investigating Health Impacts of Exposure to Harmful Algal Blooms

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Mar 24, 2025 · NCT06883227

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.