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Myelofibrosis clinical trials in Ohio

17 studies for Myelofibrosis are looking for participants at sites in Ohio.

Cities in Ohio

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

  • The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07357727

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06661915

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

  • Cleveland Clinic, Cleveland
  • The Ohio State University, Columbus
  • Taylor Cancer Research Center, Maumee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05320198

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

  • Ohio State University, Columbus
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT04176198

A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

  • University of Cincinnati, Cincinnati
  • The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06343805

Pacritinib Effectiveness in Real-world Settings

  • The Ohio State University, Columbus
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07774455

A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

  • Cleveland Clinic, Cleveland
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07623161

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

  • Cleveland Clinic, Cleveland
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT06773195

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

  • Cleveland Clinic, Cleveland
  • Ohio State University, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07441694

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

  • The Cleveland Clinic Foundation, Cleveland
  • The Ohio State University, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT05835466

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • University of Cincinnati, Cincinnati
  • The Ohio State University, Columbus
RecruitingPhase 1
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

  • Cleveland Clinic, Cleveland
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06034002

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 6007), Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT06351631

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

  • Cleveland Clinic, Cleveland
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 12, 2026 · NCT05980806

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Cincinnati
  • Massive Bio SYNERGY-AI site, Columbus
  • Massive Bio SYNERGY-AI site, Mayfield Heights
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

  • Gabrail Cancer Center, Canton
  • University of Cincinnati Medical Center, Cincinnati
  • Cleveland Clinic Cancer Center at Fairview Hospital, Cleveland
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2025 · NCT06479135

Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib

  • Gabrail Cancer Center, Canton
  • University of Cincinnati (UC), Cincinnati
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 21, 2023 · NCT05280509

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.