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Myotonic Dystrophy clinical trials recruiting in the U.S.

19 studies for Myotonic Dystrophy are recruiting participants at sites across the United States.

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Recently updated studies

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

RecruitingPhase 3
Ages 16 and older · All sexes · Updated Sep 25, 2026 · NCT07486934

Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1) Extension

RecruitingObservational study
Ages 18 to 70 · All sexes · Updated Sep 4, 2026 · NCT07700225

Trial Readiness and Endpoint Assessment in Pediatric Myotonic Dystrophy Extension

RecruitingObservational study
Ages 3 to 17 · All sexes · Updated Aug 11, 2026 · NCT06747884

DMCRN-02-001: Assessing Pediatric Endpoints in DM1

RecruitingObservational study
59 Months · All sexes · Updated Jun 10, 2026 · NCT05224778

Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

RecruitingObservational study
Ages 18 to 70 · All sexes · Updated Jun 10, 2026 · NCT03981575

Remote Assessments and Genetic Determinants of Congenital and Childhood Myotonic Dystrophy

RecruitingObservational study
Ages 0 to 17 · All sexes · Updated Jun 5, 2026 · NCT07630389

Investigating Exercise in Myotonic Dystrophy Type 2 (DM2)

Recruiting
Ages 18 to 70 · All sexes · Updated Apr 15, 2026 · NCT06716931

Remote Assessments and Genetic Determinants of Myotonic Dystrophy

RecruitingObservational study
Ages 18 to 88 · All sexes · Updated Apr 1, 2026 · NCT07505342

Study of ATX-01 in Participants With DM1

RecruitingPhase 1/2
Ages 18 to 64 · All sexes · Updated Feb 10, 2026 · NCT06300307

Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Jan 23, 2026 · NCT07362875

Biomarker Development for Muscular Dystrophies

RecruitingObservational studyHealthy volunteers welcome
Ages 5 and older · All sexes · Updated Nov 24, 2025 · NCT05019625

Extracellular RNA Biomarkers of Myotonic Dystrophy

RecruitingObservational studyHealthy volunteers welcome
Ages 5 and older · All sexes · Updated Nov 24, 2025 · NCT05020002

Cerebrospinal Fluid Biomarkers of Myotonic Dystrophy

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 24, 2025 · NCT06075693

Long-Term Development of Muscular Dystrophy Outcome Assessments

RecruitingObservational study
Ages 6 to 50 · All sexes · Updated Nov 18, 2025 · NCT05989620

Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry

RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Oct 15, 2025 · NCT00082108

Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

RecruitingPhase 2/3
Ages 6 to 45 · All sexes · Updated May 28, 2025 · NCT05004129

Myotonic Dystrophy Family Registry

RecruitingObservational study
All ages · All sexes · Updated Nov 21, 2024 · NCT02398786

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.