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Oral Cancer clinical trials in California

13 studies for Oral Cancer are looking for participants at sites in California.

Cities in California

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

  • VA Palo Alto Health Care System, Palo Alto
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06589804

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

  • USC / Norris Comprehensive Cancer Center, Los Angeles
  • Stanford Cancer Institute Palo Alto, Palo Alto
  • Sutter Medical Center Sacramento, Sacramento
  • and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07195734

DESTINY-PANTUMOUR04

  • Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

  • Tower Cancer Research Foundation, Beverly Hills
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
  • The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles
  • and 4 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
  • Los Angeles General Medical Center, Los Angeles
  • USC / Norris Comprehensive Cancer Center, Los Angeles
  • and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06980038

Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer

  • Stanford University, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06736379

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

  • Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank
  • Mercy Cancer Center - Carmichael, Carmichael
  • and 11 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

  • City of Hope Comprehensive Cancer Center, Duarte
  • City of Hope at Irvine Lennar, Irvine
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07156227

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

  • UC San Diego Moores Cancer Center, La Jolla
  • Stanford Cancer Institute Palo Alto, Palo Alto
  • UC San Diego Medical Center - Hillcrest, San Diego
  • and 2 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04333537

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

  • UC San Diego Health System - Encinitas, Encinitas
  • UC San Diego Moores Cancer Center, La Jolla
  • UC San Diego Medical Center - Hillcrest, San Diego
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

  • Tower Cancer Research Foundation, Beverly Hills
  • USC / Norris Comprehensive Cancer Center, Los Angeles
  • Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07441681

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

  • City of Hope, Duarte
  • Los Angeles Cancer Network, Glendale
  • California Research Institute, Los Angeles
  • and 3 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

Surgeon-performed Ultrasound for Real-time Guidance In Oral Cancer Surgeries - A Multicenter Randomized Controlled Trial

  • Stanford Otolaryngology - Head & Neck Surgery Department, Stanford
Recruiting
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT07203911

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.