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Ovarian Cancer clinical trials in Florida

83 studies for Ovarian Cancer are looking for participants at sites in Florida.

Cities in Florida

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

  • UF Health Cancer Institute - Gainesville, Gainesville
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07001748

A Phase I/II, First-in-Human Study to Evaluate TJ102 in Participants With Advanced or Metastatic Ovarian Cancer and Other Solid Tumors.

  • Florida Cancer Specialists Lake Nona, Orlando
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07778498

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

  • UM Sylvester Comprehensive Cancer Center at Aventura, Aventura
  • UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
  • and 6 more
RecruitingPhase 2
All ages · All sexes · Updated Nov 12, 2026 · NCT05564377

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

  • Mount Sinai Braman Comprehensive Cancer Center ( Site 0078), Miami Beach
  • Sarasota Memorial Hospital ( Site 0075), Sarasota
  • Florida Cancer Specialists East ( Site 7000), West Palm Beach
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 10, 2026 · NCT06824467

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

  • Mount Sinai Cancer Center ( Site 0029), Miami Beach
  • Orlando Health Winnie Palmer Hospital for Women and Babies ( Site 0085), Orlando
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 10, 2026 · NCT07318558

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

  • Holy Cross Hospital, Fort Lauderdale
  • Broward Health Medical Center, Fort Lauderdale
  • UF Health Cancer Institute - Gainesville, Gainesville
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT06580314

Torvutatug Samrotecan Plus Bevacizumab as First-line Maintenance in Non-Homologous Recombination Deficiency (Non-HRD) Positive Advanced Epithelial Ovarian Cancer

  • Research Site, Tamarac
  • Research Site, Tampa
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 6, 2026 · NCT07851025

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

  • Mayo Clinic Jacksonville, Jacksonville
  • University of Miami Sylvester Comprehensive Cancer Center, Miami
  • Advent Health Cancer Institute, Orlando
  • and 1 more
RecruitingPhase 2
Ages 18 and older · Women · Updated Nov 6, 2026 · NCT06787612

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

  • UM Sylvester Comprehensive Cancer Center at Aventura, Aventura
  • Florida Cancer Specialists - Bradenton Cancer Center, Bradenton
  • Morton Plant Hospital, Clearwater
  • and 26 more
Recruiting
Ages 35 to 50 · Women · Updated Nov 6, 2026 · NCT04251052

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

  • AdventHealth Cancer Institute, Orlando
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Nov 5, 2026 · NCT06586957

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

  • Mayo Clinic, Jacksonville
  • Genoma Research, Inc., Miami
  • Orlando Health, Orlando
  • and 1 more
RecruitingObservational study
Ages 18 and older · Women · Updated Nov 5, 2026 · NCT05051722

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

  • Broward Health Medical Center, Fort Lauderdale
  • Florida Cancer Specialist- South, Fort Myers
  • Baptist MD Anderson Cancer Center, Jacksonville
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07213804

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

  • USOR Florida Cancer Specialists South, Fort Myers
  • USOR Florida Cancer Specialists North, St. Petersburg
  • USOR Florida Cancer Specialists East, West Palm Beach
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05579366

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

  • Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07213791

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

  • Florida Cancer Specialists & Research Institute - Fort Myers Cancer Center - Gladiolus, Fort Myers
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06760819

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

  • Site 0241 - Florida Cancer Specialist - North, Altamonte Springs
  • Site 0173 - Mount Sinai Medical Center, Miami Beach
  • Site 0308 - Advent Health, Orlando
  • and 1 more
RecruitingPhase 2
Ages 18 and older · Women · Updated Oct 30, 2026 · NCT05128825

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

  • USA08-0, Florida City
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06953089

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • Florida Cancer Specialists - Lake Nona, Orlando
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07109726

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

  • Broward Health Medical Center, Fort Lauderdale
  • Jupiter Medical Center, Jupiter
  • Mount Sinai Medical Center, Miami Beach
  • and 2 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Oct 28, 2026 · NCT06819007

Lead-212 PSV359 Therapy for Patients With Solid Tumors

  • University of Miami, Miami
  • Biogenix, Miami
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Oct 28, 2026 · NCT06710756

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

  • Florida Cancer Specialists, Lake Mary
  • Sylvester Cancer Center, Miami
  • Mount Sinai Comprehensive Cancer Center, Miami Beach
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06161025

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

  • Mayo Clinic Jacksonville, Jacksonville
  • Moffitt Cancer Center, Tampa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT04981119

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06172478

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

  • Florida Cancer Specialists, Fort Myers
  • Mayo Clinic (Florida), Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT04657068

Torvutatug Samrotecan With or Without Bevacizumab as Maintenance Treatment of Platinum-sensitive Relapsed Epithelial Ovarian Cancer

  • Research Site, Miami
RecruitingPhase 3
Ages 18 and older · Women · Updated Oct 16, 2026 · NCT07816666

A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9

  • Florida Cancer Specialists, Orlando
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT07186842

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

  • Mount Sinai Medical Center Comprehensive Cancer Center, Miami Beach
RecruitingPhase 3
Ages 18 and older · Women · Updated Oct 15, 2026 · NCT07214779

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

  • University of Florida College of Medicine /ID# 278348, Gainesville
  • Orlando Health Cancer Institute Gynecologic Cancer Center - Orlando /ID# 278623, Orlando
  • Florida Cancer Specialists - North /ID# 278626, St. Petersburg
  • and 1 more
RecruitingPhase 2
Ages 18 and older · Women · Updated Oct 13, 2026 · NCT07059845

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

  • University of Miami, Miami
  • Sarah Cannon Research Institute - Lake Nona Florida, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06293898

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 15 and older · All sexes · Updated Oct 9, 2026 · NCT06276491

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

  • Sylvester Comprehensive Cancer Center, Univ of Miami Miller School of Medicine, Miami
RecruitingHealthy volunteers welcome
Ages 50 to 74 · Women · Updated Oct 9, 2026 · NCT00539162

Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to Standard of Care for Maintenance Treatment of Participants With Recurrent Platinum-sensitive Ovarian Cancer After Second-line (2L) Platinum-based Doublet Chemotherapy

  • Mt. Sinai Comprehensive Cancer Center, Miami
  • Sarasota Memorial Health Care System, Sarasota
RecruitingPhase 3
Ages 18 and older · Women · Updated Oct 6, 2026 · NCT07225270

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of Miami - Sylvester Comprehensive Cancer Center, Miami
  • Advent Health, Orlando
  • Florida Cancer Specialists South, Port Charlotte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.