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Pancreatic Cancer clinical trials in Illinois

31 studies for Pancreatic Cancer are looking for participants at sites in Illinois.

Cities in Illinois

Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas

  • Northwestern Medicine Chicago Proton Center, Warrenville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT02598349

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

  • University of Chicago Medical Center, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07621718

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • City of Hope Cancer Center-Chicago, Zion
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

Pancreatic Cancer Detection Consortium

  • OSF HealthCare, Peoria
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06388967

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

  • Cancer Care Specialists of Illinois, Decatur
  • Decatur Memorial Hospital, Decatur
  • Hope and Healing Clinical Research LLC, Hinsdale
  • and 2 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

DESTINY-PANTUMOUR04

  • Research Site, Decatur
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

  • Illinois Cancer Specialists, Arlington Heights
  • City of Hope, Chicago
  • OSF Medical Center, Peoria
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07562152

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • University of Illinois Cancer Center, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

  • Investigative Site US079, Chicago
  • Investigative Site US030, Evanston
  • Investigative Site US005, Naperville
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

  • OSF Saint Francis Medical Center, Peoria
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06271291

CREO - Microwave Ablation Feasibility Study

  • Rush University Medical Center, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07817147

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

  • Advocate Outpatient Center - Aurora, Aurora
  • Advocate Good Shepherd Hospital, Barrington
  • Carle BroMenn Outpatient Center, Bloomington
  • and 52 more
RecruitingObservational study
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • University of Chicago Hospital, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06465069

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

  • Northwestern University, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05372614

Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors

  • Memorial Hospital East, Shiloh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT05687123

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

  • Rush-Copley Medical Center, Aurora
  • Advocate Outpatient Center - Aurora, Aurora
  • Illinois CancerCare-Bloomington, Bloomington
  • and 45 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion

  • Northwestern University, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07594626

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

  • Research Site, Chicago
RecruitingPhase 1/2
Ages 18 to 130 · All sexes · Updated Aug 12, 2026 · NCT05417594

Pancreatic Cancer Early Detection Consortium

  • Illinois CancerCare, Bloomington
  • University of Chicago Medicine, Chicago
  • NorthShore University HealthSystem, Evanston
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy

  • Northwestern University - Robert H. Lurie Comprehensive Cancer Center, Chicago
  • Hope and Healing Cancer Services, Hinsdale
  • Orchard Healthcare Research, Skokie
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06937177

Integrated Cancer Repository for Cancer Research

  • Rush-Copley Cancer Care Center, Aurora
  • Rush-Copley Healthcare Center, Yorkville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

  • University of Illinois Hospital and Health Sciences System /ID# 251750, Chicago
  • University of Chicago Medical Center /ID# 276271, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT05005403

Evaluating the Prognostic Capability of ctDNA as a Biomarker in Pancreatic Cancer Patients Undergoing Neoadjuvant Chemotherapy

  • Northwestern Medicine Cancer Center Kishwaukee, DeKalb
  • Northwestern Medicine Cancer Center Delnor, Geneva
  • Northwestern Medicine Cancer Center Warrenville, Warrenville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT04616131

Lidocaine Infusion in Pancreatic Cancer

  • University of Illnois at Chicago, Chicago
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT04048278

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

  • Illinois CancerCare-Bloomington, Bloomington
  • Illinois CancerCare-Canton, Canton
  • Memorial Hospital of Carbondale, Carbondale
  • and 29 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06998940

Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

  • Northwestern University, Chicago
  • University of Illinois, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT06807437

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

  • Ohio State University-Telemedicine, Champaign
  • Ohio State University-Telemedicine, Chicago
  • Ohio State University Telemedicine, Quincy
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

  • OSF Saint Anthony's Health Center, Alton
  • Advocate Good Shepherd Hospital, Barrington
  • Illinois CancerCare-Bloomington, Bloomington
  • and 40 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Chicago
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source

  • Advocate Christ Medical Center, Oak Lawn
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 17, 2025 · NCT02843945

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

  • Northwestern University, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 10, 2023 · NCT05733000

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.