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Paralysis clinical trials recruiting in the U.S.

17 studies for Paralysis are recruiting participants at sites across the United States.

Paralysis is a loss of muscle function in part of your body, when messages between the brain and muscles are disrupted. Learn about causes and coping.

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Recently updated studies

Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT05094362

Understanding and Enhancing Human Health and Movement

Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 31, 2026 ยท NCT07738978

At-Home Genital Nerve Stimulation for SCI Bowel

Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 28, 2026 ยท NCT06836739

Evaluation of an Advanced Lower Extremity Neuroprostheses

Recruiting
Ages 21 to 75 ยท All sexes ยท Updated Jul 10, 2026 ยท NCT00623389

Nomad P-KAFO Study

Recruiting
Ages 18 to 89 ยท All sexes ยท Updated May 11, 2026 ยท NCT05644522

Visuomotor Prosthetic for Paralysis

Recruiting
Ages 22 to 65 ยท All sexes ยท Updated Mar 18, 2026 ยท NCT01958086

MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System

Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Mar 17, 2026 ยท NCT05936619

The ED-AWARENESS-2 Trial

Recruiting
Ages 18 and older ยท All sexes ยท Updated Mar 12, 2026 ยท NCT05534243

Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis

RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 75 ยท All sexes ยท Updated Mar 11, 2026 ยท NCT04755699

Restoring Motor and Sensory Hand Function in Tetraplegia Using a Neural Bypass System

Recruiting
Ages 22 to 65 ยท All sexes ยท Updated Mar 11, 2026 ยท NCT03680872

A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury

RecruitingPhase 1
Ages 18 to 65 ยท All sexes ยท Updated Feb 12, 2026 ยท NCT06841770

Precise Robotically IMplanted Brain-Computer InterfacE

Recruiting
Ages 22 to 75 ยท All sexes ยท Updated Jan 9, 2026 ยท NCT06429735

Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury

RecruitingMentions payment for participants
Ages 18 and older ยท All sexes ยท Updated Dec 2, 2025 ยท NCT05626816

VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration

Recruiting
Ages 22 to 75 ยท All sexes ยท Updated Nov 4, 2025 ยท NCT07224256

A Neuroprosthesis for Seated Posture and Balance

Recruiting
Ages 21 and older ยท All sexes ยท Updated Oct 27, 2025 ยท NCT01474148

Sensory Motor Transformations in Human Cortex

Recruiting
Ages 22 to 65 ยท All sexes ยท Updated May 22, 2025 ยท NCT01964261

Spinal Cord Injury Registry - North American Clinical Trials Network

RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Sep 24, 2020 ยท NCT00178724

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.