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Prediabetes clinical trials recruiting in the U.S.

68 studies for Prediabetes are recruiting participants at sites across the United States.

Prediabetes happens when your blood sugar levels are higher than normal but not high enough to be called diabetes.

Cities with the most studies

By state

Recently updated studies

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

Georgia CEAL RESTORES Family Diabetes Study

RecruitingHealthy volunteers welcome
Ages 12 and older · All sexes · Updated Sep 18, 2026 · NCT07808723

Integrating a Prescription Produce Program Within a Diabetes Prevention Program

Recruiting
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07472712

Ketogenic Diet and Diabetes Demonstration Project

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06115265

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Recruiting
Ages 20 to 65 · Women · Updated Sep 2, 2026 · NCT06735651

Peanuts for Cardiometabolic, Brain, and Intestinal Health

Recruiting
Ages 20 to 59 · All sexes · Updated Sep 2, 2026 · NCT06867198

Risk-informed Shared-decision Making Engagement Strategy for Patients With Prediabetes

Recruiting
Ages 18 to 75 · All sexes · Updated Aug 28, 2026 · NCT07553325

Human Models of Selective Insulin Resistance: Alpelisib, Part I

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Aug 24, 2026 · NCT06354088

Vitamin D and Type 2 Diabetes - Treat-To-Target

RecruitingPhase 3
Ages 30 to 74 · All sexes · Updated Aug 18, 2026 · NCT07448974

Pharmacist-Led Continuous Glucose Monitoring for Prediabetes

RecruitingObservational study
Ages 18 to 70 · All sexes · Updated Aug 10, 2026 · NCT07529366

Circadian Rhythms in Postmenopausal Women

RecruitingHealthy volunteers welcome
Ages 45 to 65 · Women · Updated Aug 10, 2026 · NCT04893226

The GRoceries Aimed at Increasing Nutrition Study

RecruitingMentions payment for participants
Ages 45 to 70 · All sexes · Updated Aug 6, 2026 · NCT07167004

Human Immunodeficiency Virus (HIV) Food Insecurities

Recruiting
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT04943861

Eating Almonds Before a Meal to Control Blood Sugar

RecruitingHealthy volunteers welcome
Ages 25 to 50 · All sexes · Updated Jul 17, 2026 · NCT07603739

Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food

Recruiting
Ages 18 to 60 · All sexes · Updated Jul 16, 2026 · NCT06988462

Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

RecruitingObservational studyHealthy volunteers welcome
Ages 14 to 18 · All sexes · Updated Jul 13, 2026 · NCT06007404

Effect of Zinc on Glucose Homeostasis

RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Jul 10, 2026 · NCT05835037

Study EHR Risk Stratification Tools

Recruiting
Ages 65 and older · All sexes · Updated Jul 9, 2026 · NCT06995378

Mechanisms for Activation of Beige Adipose Tissue in Humans

RecruitingPhase 2Healthy volunteers welcome
Ages 35 to 65 · All sexes · Updated Jul 7, 2026 · NCT04666636

Effect of Insulin Lowering on Lipogenesis

RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Jul 6, 2026 · NCT07403604

Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes?

RecruitingHealthy volunteers welcome
Ages 60 to 75 · All sexes · Updated Jul 2, 2026 · NCT07546409

Food and Metabolism Study

RecruitingHealthy volunteers welcome
Ages 40 to 70 · All sexes · Updated Jul 1, 2026 · NCT07624500

Heat and Exercise in Aging as Therapy (HEAT)

Recruiting
Ages 50 and older · All sexes · Updated Jun 23, 2026 · NCT06580964

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.