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Prediabetes clinical trials recruiting in the U.S.

64 studies for Prediabetes are recruiting participants at sites across the United States.

Prediabetes happens when your blood sugar levels are higher than normal but not high enough to be called diabetes.

Cities with the most studies

By state

Recently updated studies

Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults

Recruiting
Ages 40 to 65 · All sexes · Updated Nov 6, 2026 · NCT06025292

CGM-Enhanced DPP to Prevent Type 2 Diabetes in Adults With Prediabetes

Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07140848

Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes

Recruiting
Ages 6 to 59 · All sexes · Updated Nov 2, 2026 · NCT06482944

Neuromodulation for Metabolic Dysfunction

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07597161

New T-UP: Engaging Vulnerable Students in Diabetes Prevention

Recruiting
Ages 17 to 25 · All sexes · Updated Oct 21, 2026 · NCT07225218

SMART GOALS for Youth With Prediabetes

Recruiting
Ages 10 to 18 · All sexes · Updated Oct 20, 2026 · NCT06067451

PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT06690788

Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

RecruitingObservational studyHealthy volunteers welcome
Ages 14 to 18 · All sexes · Updated Oct 15, 2026 · NCT06007404

Insulin and Insulin Pulses During Fasting

RecruitingHealthy volunteers welcome
Ages 25 to 65 · All sexes · Updated Oct 7, 2026 · NCT06424015

How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes

Recruiting
Ages 45 to 80 · All sexes · Updated Oct 7, 2026 · NCT06817252

Pharmacist-Led Continuous Glucose Monitoring for Prediabetes

RecruitingObservational study
Ages 18 to 70 · All sexes · Updated Oct 7, 2026 · NCT07529366

Wake Forest Alzheimer's Disease Clinical Core

RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Oct 6, 2026 · NCT03140865

Mediterranean Diet and Blood Sugar Study

Recruiting
Ages 25 to 65 · All sexes · Updated Oct 5, 2026 · NCT07229781

Effects of Hourly Stair-Climbing Exercise Snacks on Metabolic and Vascular Health in Adults With Prediabetes

Recruiting
Ages 18 to 69 · All sexes · Updated Sep 29, 2026 · NCT07847684

A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP) and Follow Up PP CARE

Recruiting
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05909046

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

Georgia CEAL RESTORES Family Diabetes Study

RecruitingHealthy volunteers welcome
Ages 12 and older · All sexes · Updated Sep 18, 2026 · NCT07808723

Integrating a Prescription Produce Program Within a Diabetes Prevention Program

Recruiting
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07472712

Ketogenic Diet and Diabetes Demonstration Project

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06115265

Peanuts for Cardiometabolic, Brain, and Intestinal Health

Recruiting
Ages 20 to 59 · All sexes · Updated Sep 2, 2026 · NCT06867198

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Recruiting
Ages 20 to 65 · Women · Updated Sep 2, 2026 · NCT06735651

Risk-informed Shared-decision Making Engagement Strategy for Patients With Prediabetes

Recruiting
Ages 18 to 75 · All sexes · Updated Aug 28, 2026 · NCT07553325

Human Models of Selective Insulin Resistance: Alpelisib, Part I

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Aug 24, 2026 · NCT06354088

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.