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Prostate Cancer clinical trials in Florida

100 studies for Prostate Cancer are looking for participants at sites in Florida.

Cities in Florida

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

  • Moffitt Cancer Center-International Plaza, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • Moffitt Cancer Center, Tampa
  • and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Nov 13, 2026 · NCT04423211

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Holy Cross Hospital, Fort Lauderdale
  • Orlando Health Cancer Institute, Orlando
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03866382

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

  • University of Miami, Miami
  • AdventHealth, Orlando
  • Advanced Urology Institute, Oxford
Recruiting
Ages 18 and older · Men · Updated Nov 12, 2026 · NCT06511141

Evaluating In Home Cancer Therapy Versus In Clinic Cancer Therapy in Black Men With Locally Advanced, Biochemically Recurrent and Metastatic Prostate Cancer

  • Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · Men · Updated Nov 6, 2026 · NCT07073794

WATER IV PCa (AS Sub-study)

  • Advanced Research, Delray Beach
  • University of Miami, Miami
  • Trophy Point Urology, Tampa
Recruiting
Ages 45 and older · Men · Updated Nov 6, 2026 · NCT07650448

A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials

  • University of Florida, Gainesville
  • Mayo Clinic in Florida, Jacksonville
  • University of Miami, Miami
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Nov 5, 2026 · NCT05655494

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
  • Morton Plant Hospital, Clearwater
  • and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

  • Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07114601

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • Jupiter Medical Center, Jupiter
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06632977

A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)

  • SSAK Partners, LLC, Coral Springs
RecruitingPhase 3
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT07723248

A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer

  • Florida Cancer Specialists & Research Institute, Sarasota
RecruitingPhase 1
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT07746713

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

  • Malcom Randall Veterans Administration Medical Center, Gainesville
RecruitingPhase 3
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT06931340

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT06800313

A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07319871

A Study of JNJ-101556143 in Participants With Metastatic Prostate Cancer

  • Advanced Urology Institute, Largo
RecruitingPhase 2
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT07832292

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT07082920

A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

  • Sarah Cannon Research Institute @ Florida Cancer, Orlando
RecruitingPhase 1
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT05800665

Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance

  • Desai Sethi Urology Institute, Miami
  • Sylvester Comprehensive Cancer Center, Miami
RecruitingPhase 4
Ages 18 and older · Men · Updated Nov 2, 2026 · NCT07278362

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

  • Biogenix Molecular, LLC, Miami
RecruitingPhase 1
Ages 18 and older · Men · Updated Nov 2, 2026 · NCT07581184

A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors

  • Biogenix Molecular, LLC, Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07887971

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  • Clermont Oncology Center ( Site 0087), Clermont
  • Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0077), Jacksonville
  • Mid Florida Hematology and Oncology Center ( Site 0086), Orange City
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 30, 2026 · NCT06925737

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

  • Mayo Clinic, Jacksonville
RecruitingPhase 1
Ages 18 to 100 · Men · Updated Oct 29, 2026 · NCT05519449

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06172478

Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer

  • University of Miami Hospitals and Clinics, Miami
Recruiting
Ages 18 to 80 · Men · Updated Oct 23, 2026 · NCT07518888

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Bay Pines VA Healthcare System, Bay Pines
  • AdventHealth Daytona Beach, Daytona Beach
  • and 9 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 23, 2026 · NCT05946213

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 118, Celebration
  • Research Site 127, Margate
  • Research Site 137, Orlando
  • and 2 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT05914116

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

  • Sylvester Comprehensive Cancer Center, Miami
  • Hematology Oncology Associates of the Treasure Coast, Port Saint Lucie
RecruitingPhase 1
Ages 18 and older · Men · Updated Oct 20, 2026 · NCT07103018

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • Mount Sinai Braman Comprehensive Cancer Center ( Site 0107), Miami Beach
  • Memorial Hospital West-Memorial Cancer Institute ( Site 0109), Pembroke Pines
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT06136650

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

  • Moffitt Cancer Center, Tampa
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 20, 2026 · NCT07213674

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

  • Research Site, Miami
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 19, 2026 · NCT07611110

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

  • Research Site, Miami
  • Research Site, Tampa
RecruitingPhase 1
Ages 18 and older · Men · Updated Oct 16, 2026 · NCT06879041

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194

Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)

  • Research Site, Margate
  • Research Site, Miami
  • Research Site, Orlando
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 15, 2026 · NCT07711002

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

  • Florida Cancer Specialists, Fort Myers
  • Baptist Health South, Miami
  • AdventHealth, Orlando
RecruitingPhase 3
Ages 18 to 100 · Men · Updated Oct 15, 2026 · NCT06855277

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

  • Research Site, Miami
  • Research Site, Orlando
  • Research Site, Tampa
RecruitingPhase 1/2
Ages 18 to 99 · Men · Updated Oct 14, 2026 · NCT07590934

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  • Research Site, Hialeah
  • Research Site, Jacksonville
  • Research Site, Tampa
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 14, 2026 · NCT06952803

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

  • Mayo Clinic in Florida, Jacksonville
RecruitingEarly phase 1
Ages 18 and older · Men · Updated Oct 13, 2026 · NCT05045066

Exploring the Potential of Robotic Telesurgery in Remote Settings

  • AdventHealth, Celebration
Recruiting
Ages 18 to 90 · Men · Updated Oct 8, 2026 · NCT07130708

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
  • and 5 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 8, 2026 · NCT03678025

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.