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Prostate Cancer clinical trials in Florida

102 studies for Prostate Cancer are looking for participants at sites in Florida.

Cities in Florida

Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial

  • Baptist Health South Florida Inc, Boca Raton
Recruiting
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06496256

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

  • Moffitt Cancer Center, Tampa, Tampa
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236

DESTINY-PANTUMOUR04

  • Research Site, Coral Springs
  • Research Site, St. Petersburg
  • Research Site, West Palm Beach
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07082920

A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer

  • Florida Cancer Specialists & Research Institute, Sarasota
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07746713

A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07319871

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

  • Florida Cancer Specialists, Sarasota
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • Mount Sinai Braman Comprehensive Cancer Center ( Site 0107), Miami Beach
  • Memorial Hospital West-Memorial Cancer Institute ( Site 0109), Pembroke Pines
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men

  • Mayo Clinic in Florida, Jacksonville
Recruiting
All ages · Men · Updated Sep 25, 2026 · NCT07126548

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Holy Cross Hospital, Fort Lauderdale
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03866382

Precise Oncology Interventions in Nutrition and Training (OnPoint)

  • University of Miami, Miami
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06534918

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

  • Florida Cancer Specialists, Fort Myers
  • Baptist Health South, Miami
  • AdventHealth, Orlando
RecruitingPhase 3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

  • Moffitt Cancer Center, Tampa
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

  • Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  • Research Site, Hialeah
  • Research Site, Jacksonville
  • Research Site, Tampa
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

  • Orlando VA Medical Center, Orlando, FL, Orlando
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

  • North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville
  • Orlando VA Medical Center, Orlando, FL, Orlando
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT05011383

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  • Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0077), Jacksonville
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

  • Biogenix Molecular, LLC, Miami
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07581184

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of Miami - Sylvester Comprehensive Cancer Center, Miami
  • Advent Health, Orlando
  • Florida Cancer Specialists South, Port Charlotte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

  • University of Miami, Miami
  • AdventHealth, Orlando
  • Advanced Urology Institute, Oxford
Recruiting
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

  • Mayo Clinic- Jacksonville, Jacksonville
  • Biogenix Molecular, LLC, Miami
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy

  • Mayo Clinic in Florida, Jacksonville
Recruiting
Ages 45 and older · Men · Updated Sep 11, 2026 · NCT06940271

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Bay Pines VA Healthcare System, Bay Pines
  • Jupiter Medical Center, Jupiter
  • and 6 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

  • Florida Cancer Specialist, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

First-in-Human Study to Evaluate AZD8359 STEAP2 TCE in Participants With Prostate Cancer

  • Research Site, Orlando
RecruitingPhase 1/2
Ages 18 to 100 · Men · Updated Sep 9, 2026 · NCT07529717

A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

  • Sarah Cannon Research Institute @ Florida Cancer, Orlando
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 8, 2026 · NCT05800665

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

  • H. Lee Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
  • Morton Plant Hospital, Clearwater
  • and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer

  • Research Site, Orlando
  • Research Site, Tampa
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT07192614

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

  • Malcom Randall Veterans Administration Medical Center, Gainesville
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT06931340

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • Jupiter Medical Center, Jupiter
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06632977

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

  • Research Site, Miami
  • Research Site, Tampa
RecruitingPhase 1/2
Ages 18 to 99 · Men · Updated Aug 27, 2026 · NCT07590934

UFPTI 2403-PR12: Real-Time Volumetric Ionizing Radiation Acoustic Imaging for In-vivo Proton Treatment Monitoring in Pencil-Beam Scanning

  • Univeristy of Florida Health Proton Therapy Institute, Jacksonville
Recruiting
Ages 18 to 100 · Men · Updated Aug 27, 2026 · NCT06465966

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

  • Research Site, Miami
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 26, 2026 · NCT07611110

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

  • Mount Sinai Medical Center, Miami
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

  • Moffitt Cancer Center-International Plaza, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • Moffitt Cancer Center, Tampa
  • and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.