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Prostate Cancer clinical trials recruiting in the U.S.
487 studies for Prostate Cancer are recruiting participants at sites across the United States.
Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.
Cities with the most studies
- New York City, NY104 studies
- Houston, TX76 studies
- Boston, MA61 studies
- Los Angeles, CA61 studies
- St. Louis, MO47 studies
- San Francisco, CA45 studies
- Chicago, IL45 studies
- Seattle, WA44 studies
- Philadelphia, PA44 studies
- Nashville, TN43 studies
- Baltimore, MD42 studies
- Washington, DC38 studies
- Dallas, TX36 studies
- Cleveland, OH34 studies
- Portland, OR33 studies
- Atlanta, GA32 studies
- Durham, NC32 studies
- Baldwin Park, CA31 studies
- San Diego, CA30 studies
- Edison, NJ30 studies
- Madison, WI29 studies
- San Antonio, TX28 studies
- Omaha, NE28 studies
- Miami, FL28 studies
- Queens, NY27 studies
- Ann Arbor, MI27 studies
- Jacksonville, FL26 studies
- Columbus, OH24 studies
- Pittsburgh, PA23 studies
- Detroit, MI23 studies
- Minneapolis, MN23 studies
- Myrtle Beach, SC23 studies
- Rochester, MN22 studies
- Oklahoma City, OK21 studies
- New Haven, CT21 studies
- Milwaukee, WI20 studies
- Sacramento, CA19 studies
- Denver, CO19 studies
- Grand Rapids, MI19 studies
- Tampa, FL19 studies
By state
- Alabama12 studies
- Alaska5 studies
- Arizona42 studies
- Arkansas12 studies
- California157 studies
- Colorado40 studies
- Connecticut28 studies
- Delaware9 studies
- District of Columbia18 studies
- Florida102 studies
- Georgia41 studies
- Hawaii5 studies
- Idaho12 studies
- Illinois64 studies
- Indiana24 studies
- Iowa16 studies
- Kansas22 studies
- Kentucky19 studies
- Louisiana23 studies
- Maine4 studies
- Maryland64 studies
- Massachusetts68 studies
- Michigan57 studies
- Minnesota48 studies
- Mississippi7 studies
- Missouri48 studies
- Montana17 studies
- Nebraska28 studies
- Nevada8 studies
- New Hampshire7 studies
- New Jersey42 studies
- New Mexico10 studies
- New York127 studies
- North Carolina47 studies
- North Dakota8 studies
- Ohio65 studies
- Oklahoma24 studies
- Oregon38 studies
- Pennsylvania64 studies
- Rhode Island9 studies
- South Carolina43 studies
- South Dakota7 studies
- Tennessee50 studies
- Texas115 studies
- Utah25 studies
- Vermont5 studies
- Virginia53 studies
- Washington53 studies
- West Virginia6 studies
- Wisconsin47 studies
- Wyoming5 studies
Recently updated studies
Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial
Recruiting
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06496256Prostate Cancer Risk Identification in a Multi-Ethnic Cohort: a Prospective US-based Multi-center Validation Study of Proclarix
RecruitingObservational study
Ages 40 to 75 · Men · Updated Sep 28, 2026 · NCT07543757A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06095089Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis
RecruitingObservational study
Ages 3 and older · All sexes · Updated Sep 28, 2026 · NCT01441089IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation Therapy
RecruitingPhase 2
Ages 18 to 120 · Men · Updated Sep 28, 2026 · NCT07686380Collection of Blood From Patients With Cancer
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT00034216Precision-Based Genomics in Prostate Cancer
RecruitingObservational study
Ages 18 to 120 · Men · Updated Sep 28, 2026 · NCT04706663Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes
Recruiting
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07729150Decision Support Tool to Enhance Germline Genetic Testing for Patients With Prostate Cancer
Recruiting
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07377006DESTINY-PANTUMOUR04
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
RecruitingPhase 1/2
Ages 18 to 130 · Men · Updated Sep 25, 2026 · NCT07181161A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07082920A Study of JNJ-101556143 in Participants With Metastatic Prostate Cancer
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07832292A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07746713A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07319871Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study
RecruitingEarly phase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06759701A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men
Recruiting
All ages · Men · Updated Sep 25, 2026 · NCT07126548Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03866382A Study in Patients With Metastatic Castration-Resistant Prostate Cancer
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07719361This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07543055From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.