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Prostate Cancer clinical trials recruiting in the U.S.

487 studies for Prostate Cancer are recruiting participants at sites across the United States.

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

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Recently updated studies

Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial

Recruiting
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06496256

Prostate Cancer Risk Identification in a Multi-Ethnic Cohort: a Prospective US-based Multi-center Validation Study of Proclarix

RecruitingObservational study
Ages 40 to 75 · Men · Updated Sep 28, 2026 · NCT07543757

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06095089

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

RecruitingObservational study
Ages 3 and older · All sexes · Updated Sep 28, 2026 · NCT01441089

Collection of Blood From Patients With Cancer

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT00034216

Precision-Based Genomics in Prostate Cancer

RecruitingObservational study
Ages 18 to 120 · Men · Updated Sep 28, 2026 · NCT04706663

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236

Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes

Recruiting
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07729150

Decision Support Tool to Enhance Germline Genetic Testing for Patients With Prostate Cancer

Recruiting
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07377006

DESTINY-PANTUMOUR04

RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

RecruitingPhase 1/2
Ages 18 to 130 · Men · Updated Sep 25, 2026 · NCT07181161

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07082920

A Study of JNJ-101556143 in Participants With Metastatic Prostate Cancer

RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07832292

A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer

RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07746713

A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07319871

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

A Study in Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07719361

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.