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Psoriatic Arthritis clinical trials recruiting in the U.S.

32 studies for Psoriatic Arthritis are recruiting participants at sites across the United States.

Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. Find out about symptoms and treatment.

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Recently updated studies

A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07321873

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

RecruitingPhase 3
Ages 3 and older · All sexes · Updated Sep 25, 2026 · NCT06663332

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06671483

Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 14, 2026 · NCT07486960

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06641089

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06671496

Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07286058

Deucravacitinib-TNFi Combination Therapy for Difficult-to-Control Psoriatic Disease

RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Sep 1, 2026 · NCT07280702

A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

RecruitingPhase 4
Ages 18 and older · Women · Updated Aug 28, 2026 · NCT07654751

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

RecruitingObservational study
Up to age 21 · All sexes · Updated Aug 27, 2026 · NCT02418442

Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders

Recruiting
Ages 18 to 100 · All sexes · Updated Aug 10, 2026 · NCT07180537

Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07138898

A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT07290036

Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy

Recruiting
All ages · All sexes · Updated Jun 10, 2026 · NCT06586281

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

RecruitingObservational study
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT04751396

A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Apr 3, 2026 · NCT06454188

Rheumatology Patient Registry and Biorepository

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Feb 13, 2026 · NCT04402086

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Jan 22, 2026 · NCT04806620

Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT06865105

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.