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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

RecruitingObservational study

Who can join

Up to age 21 · All sexes

Full eligibility criteria
Inclusion Criteria:

1. Onset of rheumatic disease prior to age 16 years for JIA and onset prior to age 19 years for all other rheumatic diseases (see appendix A).
2. Subject (and/or parent/legal guardian when required) is able to provide written informed consent and willing to comply with study procedures.
3. Subject and/or parent/legal guardian is willing to be contacted in the future by study staff.

Exclusion Criteria:

1\. Greater than 21 years of age at the time of enrollment.

About the study

Continuation of the CARRA Registry as described in the protocol will support data collection on patients with pediatric-onset rheumatic diseases. The CARRA Registry will form the basis for future CARRA studies. In particular, this observational registry will be used to answer pressing questions about therapeutics used to treat pediatric rheumatic diseases, including safety questions.

Sponsor: Duke University · Participants: 20,000 · Started: 2015-07

Contact the study team

Official record on ClinicalTrials.gov — NCT02418442

Locations in the U.S.

AlabamaUniversity of Alabama at Birmingham, Birmingham
ArizonaPhoenix Children's Hospital, Phoenix
CaliforniaChildren's Hospital of Los Angeles, Los Angeles (Not yet recruiting)
Mattel Children's Hospital at University of California Los Angeles, Los Angeles
Stanford University Medical Center, Palo Alto
Rady Children's Hospital San Diego, San Diego
University of California at San Francisco Medical Center, San Francisco
ColoradoThe Children's Hospital of Colorado, Aurora
ConnecticutConnecticut Children's Medical Center, Hartford
District of ColumbiaChildrens National Medical Center, Washington D.C.
FloridaUniversity of Florida - Shand's Children's Hospital, Gainesville
Nemours Children's Hospital, Orlando
Johns Hopkins All Children's Hospital, St. Petersburg
GeorgiaEmory Children's Center, Atlanta
Georgia Regents University Medical Center, Augusta
IllinoisAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago
University of Chicago Medical Center, Chicago
IndianaIndiana University School of Medicine, Indianapolis
IowaThe University of Iowa Hospitals and Clinics (University of Iowa Children's Hospital), Iowa City
KentuckyUniversity of Louisville Schoole of Medicine, Louisville
MassachusettsBoston Children's Hospital, Boston
Massachusetts General Hospital for Children, Boston
Tufts Medical Center, Boston
MichiganUniversity of Michigan, Ann Arbor
Helen Devos Children's Hospital, Grand Rapids
MinnesotaUniversity of Minnesota, Minneapolis
Mayo Clinic, Rochester
MississippiUniversity of Mississippi Medical Center, Jackson
MissouriChildren's Mercy Hospital, Kansas City
Saint Louis Children's Hospital, St Louis
New JerseyHackensack University Medical Center, Hackensack
Goryeb Children's Hospital, Morristown
Robert Wood Johnson Medical School, New Brunswick
The Pediatric Specialty Center at Saint Barnabas, West Orange
New YorkAlbany Medical College, Albany
Cohen Children's Medical Center of New York, Lake Success
Children's Hospital at Montefiore, New York
Columbia University Medical Center, New York
Hospital for Special Surgery, New York
University of Rochester, Rochester
North CarolinaUniversity of North Carolina at Chapel Hill, Chapel Hill
Levine Children's Hospital / Carolinas Medical Center, Charlotte
Duke Children's Hospital & Health Center, Durham
Wake Forest Baptist Brenner Children's Hospital, Winston-Salem
North DakotaSanford Health, Fargo
OhioAkron Children's Hospital, Akron
Cincinnati Children's Hospital Medical Center, Cincinnati
Cleveland Clinic Foundation, Cleveland
Metrohealth Medical Center, Cleveland
Nationwide Children's Hospital, Columbus
OregonRandall Children's Hospital at Legacy Emanuel, Portland
PennsylvaniaPenn State Children's Hospital, Hershey
Children's Hospital of Philadelphia, Philadelphia
Saint Christopher's Hospital for Children, Philadelphia
Children's Hospital of Pittsburgh UPMC, Pittsburgh
Rhode IslandHasbro Children's Hospital, Providence
South CarolinaMedical University of South Carolina Children's Hospital, Charleston
TennesseeMonroe Carrell Jr. Children's Hospital at Vanderbilt, Nashville
TexasUniversity of Texas Southwestern Medical Center Dallas, Dallas
Baylor College of Medicine Pediatric Immunology Allergy Rheumatology, Houston
UtahUniversity of Utah Hospitals and Clinics (Primary Children's Hospital), Salt Lake City
VermontUniversity of Vermont Medical Center, Burlington
VirginiaChildren's Hospital of the King's Daughters, Norfolk
WashingtonSeattle Children's Hospital, Seattle
WisconsinUniversity of Wisconsin, American Family Children's Hospital, Madison
Children's Hospital Of Wisconsin, Wauwatosa

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.