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Pulmonary Hypertension clinical trials recruiting in the U.S.
55 studies for Pulmonary Hypertension are recruiting participants at sites across the United States.
Pulmonary hypertension (PH) is high blood pressure in the arteries to your lungs. It makes your heart work harder, which can lead to heart failure.
Cities with the most studies
- Philadelphia, PA11 studies
- Aurora, CO9 studies
- Boston, MA8 studies
- Kansas City, KS8 studies
- Cincinnati, OH8 studies
- New York City, NY8 studies
- Rochester, MN7 studies
- Salt Lake City, UT7 studies
- Washington, DC7 studies
- Charleston, SC7 studies
- Houston, TX7 studies
- Indianapolis, IN7 studies
- Phoenix, AZ7 studies
- Bend, OR6 studies
- Louisville, KY6 studies
- Durham, NC6 studies
- Atlanta, GA6 studies
- Los Angeles, CA6 studies
- Rochester, NY5 studies
- Providence, RI5 studies
- Richmond, VA5 studies
- Dallas, TX5 studies
- San Francisco, CA5 studies
- Chicago, IL5 studies
- Pittsburgh, PA4 studies
- Orlando, FL4 studies
- Baltimore, MD4 studies
- Sacramento, CA4 studies
- Detroit, MI4 studies
- Minneapolis, MN4 studies
- Cleveland, OH4 studies
- Albuquerque, NM4 studies
- Portland, OR4 studies
- Omaha, NE4 studies
- Nashville, TN4 studies
- Birmingham, AL4 studies
- Ann Arbor, MI4 studies
- New Orleans, LA3 studies
- Little Rock, AR3 studies
- Oklahoma City, OK3 studies
By state
- Alabama4 studies
- Arizona8 studies
- Arkansas3 studies
- California13 studies
- Colorado11 studies
- Connecticut3 studies
- District of Columbia5 studies
- Florida12 studies
- Georgia6 studies
- Illinois6 studies
- Indiana7 studies
- Kansas8 studies
- Kentucky7 studies
- Louisiana5 studies
- Maryland6 studies
- Massachusetts8 studies
- Michigan9 studies
- Minnesota8 studies
- Missouri5 studies
- Nebraska4 studies
- New Jersey4 studies
- New Mexico4 studies
- New York9 studies
- North Carolina8 studies
- Ohio12 studies
- Oklahoma4 studies
- Oregon9 studies
- Pennsylvania13 studies
- Rhode Island5 studies
- South Carolina9 studies
- Tennessee7 studies
- Texas8 studies
- Utah7 studies
- Virginia7 studies
- Wisconsin3 studies
Recently updated studies
Natural History of Sickle Cell Disease
RecruitingObservational study
Ages 2 to 90 · All sexes · Updated Nov 12, 2026 · NCT00081523Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Nov 12, 2026 · NCT01730092An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07234032A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07214376Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06911632HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07123779De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
RecruitingPhase 4
0 Months – 1 Month · All sexes · Updated Oct 29, 2026 · NCT05213676Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Oct 27, 2026 · NCT07473700Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT07179380Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT07318597Pulmonary Hypertension (PH) Biorepository for Translational Research
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Oct 22, 2026 · NCT07647549Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT07132788A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Oct 14, 2026 · NCT07285655A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Oct 8, 2026 · NCT07175038Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
RecruitingHealthy volunteers welcome
1 Month – 5 Months · All sexes · Updated Oct 6, 2026 · NCT06373289Early Intervention With Inhaled Treprostinil Among Patients With Exercise-Induced Pulmonary Hypertension (EPIH)
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07837830A Phase 3 Trial of Inhaled Mosliciguat in PH-ILD (PHrontier)
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 11, 2026 · NCT07816185A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06388421Development of an Algorithm to Detect Pulmonary Hypertension Using an Electronic Stethoscope
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05873387Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07136623Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)
RecruitingPhase 4
28 Days · All sexes · Updated Aug 18, 2026 · NCT07322133Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
RecruitingPhase 2
Ages 8 to 60 · All sexes · Updated Aug 14, 2026 · NCT03630211Xenon MRI Pulm Hypertension
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 10, 2026 · NCT04991454From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.