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Pulmonary Hypertension clinical trials recruiting in the U.S.
55 studies for Pulmonary Hypertension are recruiting participants at sites across the United States.
Pulmonary hypertension (PH) is high blood pressure in the arteries to your lungs. It makes your heart work harder, which can lead to heart failure.
Cities with the most studies
- Philadelphia, PA10 studies
- Aurora, CO9 studies
- Cincinnati, OH8 studies
- Indianapolis, IN8 studies
- Phoenix, AZ8 studies
- Kansas City, KS8 studies
- Bend, OR7 studies
- New York City, NY7 studies
- Rochester, MN7 studies
- Houston, TX7 studies
- Charleston, SC7 studies
- Boston, MA7 studies
- Los Angeles, CA6 studies
- Louisville, KY6 studies
- Salt Lake City, UT6 studies
- Atlanta, GA6 studies
- Rochester, NY5 studies
- Chicago, IL5 studies
- Orlando, FL5 studies
- Durham, NC5 studies
- Washington, DC5 studies
- Providence, RI5 studies
- Sacramento, CA4 studies
- San Francisco, CA4 studies
- Denver, CO4 studies
- Albuquerque, NM4 studies
- Dallas, TX4 studies
- Birmingham, AL4 studies
- Portland, OR4 studies
- Cleveland, OH4 studies
- Richmond, VA4 studies
- Pittsburgh, PA4 studies
- Minneapolis, MN4 studies
- Detroit, MI4 studies
- Omaha, NE4 studies
- Ann Arbor, MI4 studies
- Nashville, TN4 studies
- Tampa, FL3 studies
- Knoxville, TN3 studies
- Oklahoma City, OK3 studies
By state
- Alabama4 studies
- Arizona9 studies
- California14 studies
- Colorado12 studies
- District of Columbia4 studies
- Florida12 studies
- Georgia6 studies
- Illinois6 studies
- Indiana8 studies
- Kansas8 studies
- Kentucky7 studies
- Louisiana5 studies
- Maryland5 studies
- Massachusetts7 studies
- Michigan9 studies
- Minnesota8 studies
- Missouri4 studies
- Nebraska4 studies
- New Jersey4 studies
- New Mexico4 studies
- New York8 studies
- North Carolina7 studies
- Ohio12 studies
- Oklahoma4 studies
- Oregon10 studies
- Pennsylvania13 studies
- Rhode Island5 studies
- South Carolina9 studies
- Tennessee7 studies
- Texas7 studies
- Utah6 studies
- Virginia6 studies
- Wisconsin3 studies
Recently updated studies
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT01730092Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07318597Early Intervention With Inhaled Treprostinil Among Patients With Exercise-Induced Pulmonary Hypertension (EPIH)
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07837830Natural History of Sickle Cell Disease
RecruitingObservational study
Ages 2 to 90 · All sexes · Updated Sep 16, 2026 · NCT00081523A Phase 3 Trial of Inhaled Mosliciguat in PH-ILD (PHrontier)
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 11, 2026 · NCT07816185Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 8, 2026 · NCT07473700A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Sep 2, 2026 · NCT07285655A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Recruiting
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06911632Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07132788DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06388421Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
RecruitingHealthy volunteers welcome
1 Month – 5 Months · All sexes · Updated Aug 26, 2026 · NCT06373289Development of an Algorithm to Detect Pulmonary Hypertension Using an Electronic Stethoscope
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05873387Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07136623Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)
RecruitingPhase 4
28 Days · All sexes · Updated Aug 18, 2026 · NCT07322133De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
RecruitingPhase 4
0 Months – 1 Month · All sexes · Updated Aug 18, 2026 · NCT05213676A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Recruiting
Ages 18 to 85 · All sexes · Updated Aug 18, 2026 · NCT07214376HS235 Study in Obese Participants With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (HFpEF)
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07123779Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT07179380Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
RecruitingPhase 2
Ages 8 to 60 · All sexes · Updated Aug 14, 2026 · NCT03630211An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07234032Xenon MRI Pulm Hypertension
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 10, 2026 · NCT04991454A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Aug 10, 2026 · NCT07175038Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension
RecruitingPhase 1
Ages 18 to 80 · All sexes · Updated Jul 31, 2026 · NCT06770023The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease
Recruiting
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT07561034From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.