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Rectal Cancer clinical trials in Texas

18 studies for Rectal Cancer are looking for participants at sites in Texas.

Cities in Texas

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

  • Texas Oncology - DFW ( Site 8002), Dallas
  • UT Southwestern Medical Center ( Site 0059), Dallas
  • Texas Oncology - Northeast Texas ( Site 8001), Denison
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06997497

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • MD Anderson, Houston
  • NEXT Dallas, Irving
  • NEXT Oncology San Antonio, San Antonio
  • and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

  • The University of Texas MD Anderson Cancer Center - Texas Medical Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • UT Southwestern Medical Center, Dallas
  • DHR Health Advance Care Center, Edinburg
  • The Center for Cancer and Blood Disorders, Forth Worth
  • and 1 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

  • Audie L Murphy VA Hospital, San Antonio
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

  • University of Texas Health Science Center at Houston, Houston
Recruiting
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07351071

Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer

  • M D Anderson Cancer Center, Houston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT02107105

Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001

  • UT Health San Antonio MD Anderson Cancer Center, San Antonio
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05254327

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

  • UT MD Anderson Cancer Center, Houston
  • Scott and White Memorial Hospital, Temple
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485

Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery

  • UT Southwestern Medical Center, Dallas
RecruitingPhase 2/3
Ages 18 to 80 · All sexes · Updated Jun 30, 2026 · NCT03051464

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

  • The University of Texas MD Anderson Cancer Center, Houston
  • NEXT Oncology, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

  • Texas Oncology - Central/South Texas, Austin
  • Texas Oncology - Gulf Coast, Beaumont
  • Texas Oncology - Northeast Texas, Tyler
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576

Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

  • M D Anderson Cancer Center, Houston
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT03594630

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • MD Anderson Cancer Center, Houston
  • NEXT Oncology, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Trial Utilizing Metronidazole to Optimize the Microbiome of Rectal Adenocarcinoma Undergoing Neoadjuvant Therapy

  • MD Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT06569368

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

  • Md Anderson Cancer Center, Houston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

Sample Collection for Ongoing Research and Product Evaluation Study

  • Natera, Inc., Austin
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT07318051

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Dallas
  • Massive Bio SYNERGY-AI site, Houston
  • Massive Bio SYNERGY-AI site, Temple
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.