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Rheumatoid Arthritis clinical trials recruiting in the U.S.

60 studies for Rheumatoid Arthritis are recruiting participants at sites across the United States.

Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, and stiffness in your joints. Your risk increases as you become an older adult.

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Recently updated studies

Pain Phenotyping of Rheumatic Diseases - An Observational Study

RecruitingObservational studyHealthy volunteers welcome
Ages 9 to 85 · All sexes · Updated Nov 12, 2026 · NCT07829497

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04751396

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03816345

A Study of AZD0120 in Autoimmune Diseases

RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Nov 10, 2026 · NCT07295847

Study of PTC844 in Participants With Active Rheumatoid Arthritis

RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Nov 6, 2026 · NCT07779616

Effect of Anti-inflammatory Diet in Rheumatoid Arthritis

Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT04748809

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Recruiting
Ages 21 and older · All sexes · Updated Nov 4, 2026 · NCT06631638

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Oct 30, 2026 · NCT06733935

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Oct 28, 2026 · NCT07201558

A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis

RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Oct 23, 2026 · NCT07412704

An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07620392

HRV Variation in Rheumatoid Arthritis

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07878975

Phase 1b/2 Study of IV Sarilumab in Adult With RA

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07704580

A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT07276581

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT06972446

A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 5, 2026 · NCT06570798

Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis

Recruiting
Ages 18 to 64 · All sexes · Updated Oct 5, 2026 · NCT07524244

RA-PRO PRAGMATIC TRIAL

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT04692493

Exactech Shoulder Post Market Clinical Follow-up Study

RecruitingObservational study
Ages 21 and older · All sexes · Updated Sep 17, 2026 · NCT05603728

FT839 in Autoimmune Diseases

RecruitingPhase 1/2
Ages 18 to 70 · All sexes · Updated Sep 2, 2026 · NCT07800871

Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Aug 19, 2026 · NCT05277025

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.