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Rheumatoid Arthritis clinical trials recruiting in the U.S.

58 studies for Rheumatoid Arthritis are recruiting participants at sites across the United States.

Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, and stiffness in your joints. Your risk increases as you become an older adult.

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Recently updated studies

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Recruiting
Ages 21 and older · All sexes · Updated Sep 25, 2026 · NCT06631638

RA-PRO PRAGMATIC TRIAL

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT04692493

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345

A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis

RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT07412704

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06972446

An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07620392

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 18, 2026 · NCT07201558

Exactech Shoulder Post Market Clinical Follow-up Study

RecruitingObservational study
Ages 21 and older · All sexes · Updated Sep 17, 2026 · NCT05603728

FT839 in Autoimmune Diseases

RecruitingPhase 1/2
Ages 18 to 70 · All sexes · Updated Sep 2, 2026 · NCT07800871

A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 21, 2026 · NCT06570798

Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Aug 19, 2026 · NCT05277025

Phase 1b/2 Study of IV Sarilumab in Adult With RA

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07704580

Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders

Recruiting
Ages 18 to 100 · All sexes · Updated Aug 10, 2026 · NCT07180537

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Aug 7, 2026 · NCT06733935

A Study of AZD0120 in Autoimmune Diseases

RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Jul 28, 2026 · NCT07295847

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Jul 20, 2026 · NCT07237659

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

RecruitingObservational study
Ages 35 to 79 · All sexes · Updated Jul 14, 2026 · NCT07315997

A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07115745

Early Rheumatoid Arthritis Lung Disease Study

RecruitingObservational study
Ages 19 to 90 · All sexes · Updated Jul 9, 2026 · NCT03192267

Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07138898

Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis

Recruiting
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07293871

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.