Home › Fibromyalgia › NCT05277025
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Who can join
Ages 18 to 70 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Ages 18-70 * Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM * Fulfills the 2010 ACR-EULAR classification criteria for RA * Healthy volunteers: No significant pain/fatigue/depression/anxiety. Exclusion Criteria: * Diabetes * Cancer * Advanced liver, kidney or cardiovascular disease * Neuropathic pain
About the study
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Sponsor: University of Florida · Participants: 150 · Started: Mar 22, 2022
Contact the study team
- Roland Staud, M.D. · Phone: 352-294-8200
- Melyssa M Godfrey, BS · Phone: 352-265-8901
Official record on ClinicalTrials.gov — NCT05277025
Locations in the U.S.
| Florida | University of Florida, Gainesville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.