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Sickle Cell Disease clinical trials in Maryland

17 studies for Sickle Cell Disease are looking for participants at sites in Maryland.

Cities in Maryland

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

  • The Johns Hopkins University School of Medicine, Baltimore
RecruitingPhase 3
Ages 12 to 100 · All sexes · Updated Nov 10, 2026 · NCT06439082

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Nov 5, 2026 · NCT05904093

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

  • Center for Cancer and Blood Disorders, Bethesda
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07224360

Blood Sampling for Research Related to Sickle Cell Disease

  • National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Oct 26, 2026 · NCT00542230

Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1
Ages 18 to 90 · All sexes · Updated Oct 21, 2026 · NCT07566494

Virtual Reality for SCD VOC

  • University of Maryland Medical Center, Stoler Infusion Center, Baltimore
Recruiting
Ages 18 to 88 · All sexes · Updated Oct 16, 2026 · NCT07674277

The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

  • University of Maryland School of Medicine - Baltimore- Site Number : 8400041, Baltimore
RecruitingPhase 3
Ages 10 to 65 · All sexes · Updated Oct 15, 2026 · NCT06975865

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

  • National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1/2
Ages 4 to 65 · All sexes · Updated Oct 13, 2026 · NCT07599176

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

  • University of Maryland, Baltimore
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Oct 8, 2026 · NCT06699849

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

  • National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Oct 2, 2026 · NCT03937817

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling

  • National Institutes of Health Clinical Center, Bethesda
RecruitingEarly phase 1
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT06313398

Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease

  • National Institutes of Health Clinical Center, Bethesda
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Sep 18, 2026 · NCT05170412

Study to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell Disease

  • National Institutes of Health Clinical Center, Bethesda
RecruitingObservational study
Ages 2 to 99 · All sexes · Updated Sep 11, 2026 · NCT06944067

SCD Stem Cell Mobilization and Apheresis Using Motixafortide

  • National Heart, Blood and Lung Institute-Cellular and Molecular Therapy Branch, Bethesda
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06442761

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

  • Local Institution - 0064, Baltimore
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

  • Johns Hopkins University Hemophilia Treatment Center, Baltimore
RecruitingObservational study
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

  • University of Maryland Medical Systems, Baltimore
Recruiting
Ages 18 and older · All sexes · Updated Dec 24, 2025 · NCT06184126

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.