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Small Cell Lung Cancer clinical trials in California

36 studies for Small Cell Lung Cancer are looking for participants at sites in California.

Cities in California

A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]

  • GSK Investigational Site, Los Angeles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07099898

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

  • City of Hope National Medical Center, Duarte
  • UC San Diego Medical Center - Encinitas, Encinitas
  • City of Hope Lennar Foundation Cancer Center, Irvine
  • and 9 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07476287

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

  • University of California - Los Angeles, Los Angeles
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Sep 28, 2026 · NCT06586957

DESTINY-PANTUMOUR04

  • Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

  • Kivu Trial Site, Santa Monica
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07229313

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

  • Precision NextGen Oncology, Beverly Hills
  • OPN Healthcare, Inc, Glendale
  • University of Southern California, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

  • City of Hope National Medical Center /ID# 281322, Duarte
  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 281396, Irvine
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

  • START Los Angeles, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

  • Beverly Hills Cancer Center, Beverly Hills
  • City of Hope Cancer Center, Duarte
  • University of California Irvine Medical Center, Orange
  • and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

  • Los Alamitos Hematology/Oncology Medical Group, Glendale
  • MemorialCare Todd Cancer Institute, Long Beach
  • Valkyrie Clinical Trials, Los Angeles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07625644

A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

  • Valkyrie Clinical Trials, Inc., Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07459634

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of San Diego Moores Cancer Center, La Jolla
  • UCLA Jonsson Comprehensive Cancer Center, Los Angeles
  • USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

  • University of California San Diego, La Jolla
  • UC Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07218146

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

  • Avenzo Therapeutics Recruiting Site, Los Angeles
  • Avenzo Therapeutics Recruiting Site, Los Angeles
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

  • University of California LA, Los Angeles
RecruitingPhase 1/2
Ages 18 to 100 · All sexes · Updated Aug 27, 2026 · NCT06726148

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

  • Precision NextGen Oncology and Research Center, Beverly Hills
  • Cedars Sinai Medical Center, Los Angeles
  • UCLA - David Geffen School of Medicine, Santa Monica
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06892548

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

  • University of Southern California, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06922539

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

  • The Oncology Institute of Hope and Innovation, Long Beach
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06095505

A Study of MGC026 in Participants With Advanced Solid Tumors

  • The Angeles Clinic and Research Institute, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

  • Clinical Research Providence Medical Foundation, Fullerton
  • UCLA Hematology-Oncology, Los Angeles
  • UCSF Mission Bay Mission Hall, San Francisco
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06203210

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

  • Valkyrie Clinical Trials, Los Angeles
  • University of California San Francisco, San Francisco
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT05882058

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

  • City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte
  • IP Address: City of Hope Investigational Drug Services(IDS), Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

  • City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte
  • USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT05652686

LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)

  • University of California, Davis, Sacramento
Recruiting
Ages 18 and older · All sexes · Updated Jul 8, 2026 · NCT06103682

Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

  • University of Southern California, Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT06598306

A Study of LY4175408 in Participants With Advanced Cancer

  • Stanford Medicine Cancer Center, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

  • Start Lacn, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07517198

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

  • Beckman Research Institute of City of Hope, Duarte
  • VA Medical Center, Fresno, Fresno
  • Santa Clara Valley Medical Center, Fruitdale
  • and 5 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

  • Loma Linda University Medical Center, Loma Linda
  • Eisenhower Medical Center, Rancho Mirage
  • University of California Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT06769126

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

  • VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 11, 2026 · NCT06681220

Engagement of Veterans With Lung Cancer

  • Veterans Affairs Palo Alto Health Care System (VAPAHCS), Palo Alto
Recruiting
Ages 18 and older · All sexes · Updated Mar 3, 2026 · NCT07219251

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

  • Providence Medical Foundation (site 209), Santa Rosa
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 125, Los Angeles
  • Research Site 133, Los Angeles
  • Research Site 103, Los Angeles
  • and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

  • Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles
RecruitingPhase 2
All ages · All sexes · Updated Nov 17, 2025 · NCT05588388

A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung Cancer

  • Zelgen Site 105, Orange
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Aug 6, 2025 · NCT06592638

A Multicenter Cancer Biospecimen Collection Study

  • Curebase, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2025 · NCT04510129

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.