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Small Cell Lung Cancer clinical trials recruiting in the U.S.

100 studies for Small Cell Lung Cancer are recruiting participants at sites across the United States.

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Recently updated studies

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT06805825

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07488676

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT03460977

A Study of Armored CAR T Cells in People With Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07783477

BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07625644

Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)

RecruitingPhase 2
Ages 18 to 120 · All sexes · Updated Nov 12, 2026 · NCT06228066

A Study to Test Obrixtamig in Combination With Pumitamig in People With Advanced Small Cell Lung Cancer (Dareon®-Rosetta35)

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07843940

A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07099898

A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

RecruitingPhase 1
Ages 18 to 120 · All sexes · Updated Nov 10, 2026 · NCT06066138

A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07459634

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
Ages 19 and older · All sexes · Updated Nov 5, 2026 · NCT06586957

MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT05903092

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT03556228

A Study of Alisertib and Paclitaxel in Patients With Small Cell Lung Cancer (SCLC)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07465757

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT06807632

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

RecruitingPhase 2
Ages 18 to 120 · All sexes · Updated Oct 29, 2026 · NCT06503146

A Study of MGC026 in Participants With Advanced Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT06242470

PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT04199741

SMARCA4/2 Inhibitor for POU2F3-Positive SCLC

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT07551635

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.