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Small Cell Lung Cancer clinical trials in Pennsylvania

15 studies for Small Cell Lung Cancer are looking for participants at sites in Pennsylvania.

Cities in Pennsylvania

DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy

  • AHN Cancer Institute - Allegheny General, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07472517

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

  • Sidney Kimmell Cancer Center - Jefferson Health, Philadelphia
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Nov 5, 2026 · NCT06586957

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

  • Cancer Care Associates of York (site 206), York
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT03556228

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

  • Avenzo Therapeutics Recruiting Site, Philadelphia
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Oct 16, 2026 · NCT07038343

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

  • Consultants in Medical Oncology and Hematology, Broomall
  • Alliance Cancer Specialists, Media
  • Allegheny General Hospital, Pittsburgh
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07218146

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

  • St. Luke's Physician Group - St. Luke's Cancer Care Associates, Fountain Hill
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06712355

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
  • University of Pittsburgh Medical Center, Pittsburgh
  • WellSpan York Cancer Center, York
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

DESTINY-PANTUMOUR04

  • Research Site, Philadelphia
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

  • St. Lukes University Hospital /ID# 280204, Bethlehem
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer

  • Fox Chase Cancer Center, Philadelphia
  • UPMC Hillman Cancer Center, Pittsburgh
  • Guthrie, Sayre
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07057791

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

  • Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07174583

Tempus Small Cell Lung Cancer Observational Study (Sculptor)

  • Cancer Care Association of York, York
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT05257551

Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

  • Fox Chase Cancer Center, Philadelphia
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT05800587

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia
  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 11, 2026 · NCT06681220

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

  • University of Pennsylvania, Philadelphia
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.