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Soft Tissue Sarcoma clinical trials in California
39 studies for Soft Tissue Sarcoma are looking for participants at sites in California.
Cities in California
- Los Angeles13 studies
- Baldwin Park7 studies
- Santa Monica7 studies
- Mountain View6 studies
- Orange6 studies
- San Francisco5 studies
BostonGene and Exigent Genomic INsight Study
- Stockton Hematology Oncology Medical Group, Stockton
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06272864Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma
- Children's Hospital of Los Angeles, Los Angeles
- Lucile Packard Children's Hospital, Palo Alto
RecruitingPhase 1/2
Ages 2 to 30 · All sexes · Updated Nov 5, 2026 · NCT05734066cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- City of Hope, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Nov 4, 2026 · NCT05366881Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05711615Distance-Based Exercise to Preserve Function and Prevent Disability
- Kaiser Permanente Dublin, Dublin
- Kaiser Permanente-Fremont, Fremont
- Kaiser Permanente Fresno Orchard Plaza, Fresno
- and 10 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07059884A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
- City of Hope - Duarte Cancer Center, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06760819Lead-212 PSV359 Therapy for Patients With Solid Tumors
- VA Greater Los Angeles Healthcare System, Los Angeles
- UCLA Department of Medicine - Hematology/Oncology, Los Angeles
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Oct 28, 2026 · NCT06710756A Study of MGC026 in Participants With Advanced Solid Tumors
- The Angeles Clinic and Research Institute, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT06242470A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma
- University of Southern California - Norris Cancer Center, Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06942442STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas
- University of California, San Francisco, San Francisco
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT06975293Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial
- City of Hope Medical Center, Duarte
RecruitingPhase 2
All ages · All sexes · Updated Oct 16, 2026 · NCT07650656A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
- Children's Hospital Los Angeles, Los Angeles
- University of California at Los Angeles, Los Angeles
RecruitingPhase 1/2
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610DESTINY-PANTUMOUR04
- Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
- Kivu Trial Site, Santa Monica
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07229313Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
- Stanford University, Palo Alto
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05732831Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
- Precision NextGen Oncology and Research, Beverly Hills
- City of Hope, Duarte
- Valkyrie Clinical Trials, Los Angeles
- and 3 more
RecruitingPhase 1
Ages 12 to 85 · All sexes · Updated Sep 8, 2026 · NCT03715933Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas
- University of California San Francisco, San Francisco
RecruitingPhase 1
Ages 5 to 40 · All sexes · Updated Sep 3, 2026 · NCT06156410A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
- USC/Norris Comprehensive Cancer Center, Los Angeles
- Sarcoma Oncology Center, Santa Monica
- University of California Los Angeles (UCLA) - Santa Monica Cancer Care, Santa Monica
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06263231Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
- Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07628634Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors
- Zai Lab Site 02003, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07374848Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
- Chao Family Comprehensive Cancer Center University of California, Irvine, Orange
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT07064018Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
- Chao Family Comprehensive Cancer Center, University of California Irvine, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06580002Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)
- University of California, Davis, Sacramento
Recruiting
Ages 18 and older · All sexes · Updated Jul 8, 2026 · NCT06103669Navigation Intervention for Adolescent and Young Adult Cancer Survivors
- KP Southern California - Department of Research & Evaluation, Pasadena
Recruiting
Ages 21 to 45 · All sexes · Updated Jul 6, 2026 · NCT07406087A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
- Precision NextGen Oncology and Research Center, Beverly Hills
- Sarcoma Oncology Center, Santa Monica
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT067891725-Day Preoperative Radiation for Soft Tissue Sarcoma
- Stanford University, Palo Alto
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06087861A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
- St Joseph Heritage Healthcare, Santa Rosa
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
- Lucille Packard Children's Hospital Stanford, Palo Alto
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated May 19, 2026 · NCT04901702Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors
- Stanford University, Palo Alto
RecruitingPhase 1
Ages 2 to 30 · All sexes · Updated May 7, 2026 · NCT06500819Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
- Beckman Research Institute of City of Hope, Duarte
- VA Medical Center, Fresno, Fresno
- Santa Clara Valley Medical Center, Fruitdale
- and 5 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Mar 10, 2026 · NCT02701153Phase II Trial of Lung Chemoemobolization
- City of Hope Medical Center, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT05672108Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
- Chao Family Comprehensive Cancer Center, University of California Irvine, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 3, 2026 · NCT07447050Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
- Sarcoma Oncology Center, Santa Monica
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT03016819A Study of MT-4561 in Patients With Various Advanced Solid Tumors
- University of Southern California, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT0694352164Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
- City of Hope, Duarte
- UC Irvine Health - Chao Family Comprehensive Cancer Center, Orange
- Stanford Hospital & Clinics, Stanford
RecruitingPhase 1/2
Ages 15 and older · All sexes · Updated Aug 12, 2025 · NCT06298916Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma
- Sarcoma Oncology Center, Santa Monica
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 24, 2025 · NCT03886311SAINT:Trabectedin, Ipilimumab and Nivolumab for Previously Treated Advanced Soft Tissue Sarcoma
- Sarcoma Oncology Research Center, Santa Monica
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 24, 2025 · NCT03138161REtroperitoneal SArcoma Registry: an International Prospective Initiative
- University of Southern California (USC), Los Angeles
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 12, 2019 · NCT03838718From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.