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Soft Tissue Sarcoma clinical trials recruiting in the U.S.
135 studies for Soft Tissue Sarcoma are recruiting participants at sites across the United States.
Soft tissue sarcoma refers to cancer that begins in the muscle, fat, vessels or tendons. It can cause a lump or swelling. See which treatments are available
Cities with the most studies
- Houston, TX32 studies
- New York City, NY20 studies
- Boston, MA18 studies
- St. Louis, MO14 studies
- Columbus, OH13 studies
- Los Angeles, CA13 studies
- Washington, DC12 studies
- Memphis, TN11 studies
- Philadelphia, PA10 studies
- Nashville, TN9 studies
- Rochester, MN9 studies
- Aurora, CO9 studies
- Queens, NY9 studies
- Atlanta, GA8 studies
- Durham, NC8 studies
- Santa Monica, CA7 studies
- Grand Rapids, MI7 studies
- Edison, NJ7 studies
- Chicago, IL7 studies
- Greenburgh, NY7 studies
- Baldwin Park, CA7 studies
- Orange, CA6 studies
- Baltimore, MD6 studies
- New Rochelle, NY6 studies
- East Norwalk, CT6 studies
- Staten Island, NY6 studies
- Dallas, TX6 studies
- Miami, FL6 studies
- Mountain View, CA6 studies
- Cincinnati, OH5 studies
- Cleveland, OH5 studies
- Pittsburgh, PA5 studies
- Arlington, VA5 studies
- Birmingham, AL5 studies
- San Francisco, CA5 studies
- Omaha, NE4 studies
- San Antonio, TX4 studies
- Portland, OR4 studies
- Minneapolis, MN4 studies
- Jacksonville, FL4 studies
By state
- Alabama5 studies
- Arizona6 studies
- California41 studies
- Colorado13 studies
- Connecticut5 studies
- District of Columbia7 studies
- Florida20 studies
- Georgia10 studies
- Illinois9 studies
- Indiana4 studies
- Iowa4 studies
- Kansas4 studies
- Kentucky3 studies
- Louisiana3 studies
- Maryland11 studies
- Massachusetts19 studies
- Michigan10 studies
- Minnesota13 studies
- Missouri15 studies
- Nebraska4 studies
- New Jersey8 studies
- New Mexico3 studies
- New York28 studies
- North Carolina13 studies
- Ohio23 studies
- Oregon4 studies
- Pennsylvania15 studies
- South Carolina3 studies
- Tennessee19 studies
- Texas37 studies
- Utah5 studies
- Virginia7 studies
- Washington3 studies
- Wisconsin5 studies
Recently updated studies
Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies
RecruitingObservational studyHealthy volunteers welcome
4 Weeks · All sexes · Updated Sep 28, 2026 · NCT01109394DESTINY-PANTUMOUR04
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
RecruitingPhase 1/2
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07229313Anti-GD2 ADC M3554 in Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06641908A Study of CRD3874-SI in People With Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06021626A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07705334FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma
RecruitingPhase 1
Ages 3 to 39 · All sexes · Updated Sep 14, 2026 · NCT06865664Biomarkers of Resiliency In Childhood Cancer Surgery
RecruitingObservational study
Ages 3 to 25 · All sexes · Updated Sep 14, 2026 · NCT06674811First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06797999Minibeam Radiation Therapy With Tungsten Slit Collimator for the Treatment of Recurrent or Metastatic Skin or Soft Tissue Tumors
Recruiting
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07062003Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
RecruitingPhase 1
Ages 12 to 85 · All sexes · Updated Sep 8, 2026 · NCT03715933Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04577014Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05732831First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06644755Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05711615Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma
RecruitingPhase 1/2
Ages 12 to 40 · All sexes · Updated Sep 3, 2026 · NCT07725380A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06760819Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas
RecruitingPhase 1
Ages 5 to 40 · All sexes · Updated Sep 3, 2026 · NCT06156410GRID Therapy for Extremity Soft Tissue Sarcoma
Recruiting
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06073067Serial MRI Scans During Radiation Therapy
Recruiting
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04188535Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue
Recruiting
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05837767Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
RecruitingObservational study
Ages 18 to 50 · Women · Updated Sep 2, 2026 · NCT06904365Actinium Therapy for Late-stage Aggressive Sarcomas
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07156565From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.