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Soft Tissue Sarcoma clinical trials in Texas

37 studies for Soft Tissue Sarcoma are looking for participants at sites in Texas.

Cities in Texas

Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma

  • UT MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06498648

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

  • The University of Texas Southwestern Medical Center - Harold C Simmons Comprehensive Cancer Center, Dallas
  • Baylor College of Medicine, Houston
RecruitingPhase 1/2
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610

DESTINY-PANTUMOUR04

  • Research Site, Dallas
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Anti-GD2 ADC M3554 in Advanced Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06641908

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
  • NEXT Oncology, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07705334

First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

  • University Of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06797999

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05732831

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

  • UT MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 12 to 85 · All sexes · Updated Sep 8, 2026 · NCT03715933

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

  • UT MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05711615

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

  • The University of Texas MD Anderson Cancer Center - Texas Medical Center, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06760819

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • The Don and Sybil Harrington Cancer Center, Amarillo
  • UT MD Anderson Cancer Center, Houston
  • Audie L Murphy VA Hospital, San Antonio
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Actinium Therapy for Late-stage Aggressive Sarcomas

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07156565

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

  • MD Anderson Cancer Center, Houston
  • NEXT Houston, Houston
  • NEXT Dallas, Irving
  • and 2 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06975293

Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

  • M D Anderson Cancer Center, Houston
RecruitingObservational study
All ages · All sexes · Updated Aug 21, 2026 · NCT01772771

Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma

  • MD Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07283731

T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 12 and older · All sexes · Updated Aug 18, 2026 · NCT06474676

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

  • Ut Southwestern Medical Center, Dallas
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07139990

A Study of MGC026 in Participants With Advanced Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
  • University of Texas Health Science Center at Houston, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

  • M D Anderson Cancer Center, Houston
Recruiting
Ages 10 and older · All sexes · Updated Aug 11, 2026 · NCT04199026

A Phase I Study of Pazopanib in Combination With Trabectedin, Ipilimumab and Nivolumab (TraPIN) in Pediatric and Young Adult Patients With Recurrent Soft Tissue Sarcomas

  • The University of Texas M. D. Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 1 to 30 · All sexes · Updated Aug 6, 2026 · NCT07444619

IDOV-Immune for Advanced Solid Tumors

  • MD Anderson Cancer Center, Houston
  • South Texas Accelerated Research Therapeutics, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma

  • MD Anderson Cancer Center, Houston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT07377747

Lead-212 PSV359 Therapy for Patients With Solid Tumors

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

  • M D Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT04771520

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT06789172

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

  • UT Southwestern Medical Center, Dallas
  • MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Iscador® P (Mistletoe) Immunotherapy for Recurrent Resectable Osteogenic Sarcoma

  • M.D. Anderson Children's Cancer Hospital, Houston
RecruitingPhase 2
Ages 8 to 30 · All sexes · Updated May 22, 2026 · NCT05726383

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

  • University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT04969835

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

  • William Beaumont Army Medical Center, Fort Bliss
Recruiting
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT06129903

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

  • M D Anderson Cancer Center, Houston
Recruiting
Ages 18 and older · All sexes · Updated Apr 15, 2026 · NCT04693377

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

  • Children's Health Dallas, Dallas
  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 2 to 30 · All sexes · Updated Feb 3, 2026 · NCT05734066

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

  • Texas Children's Hospital, Houston
RecruitingPhase 1
Ages 1 to 25 · All sexes · Updated Jan 22, 2026 · NCT04995003

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

  • Elligo Health Research, Inc., Austin
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT06943521

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

  • Mary Crowley Cancer Research, Dallas
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT04370587

BostonGene and Exigent Genomic INsight Study

  • Oncology Consultants, Houston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 17, 2025 · NCT06272864

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.