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Squamous Cell Carcinoma clinical trials recruiting in the U.S.

50 studies for Squamous Cell Carcinoma are recruiting participants at sites across the United States.

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Recently updated studies

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

RecruitingPhase 3
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT04892173

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

Intratumoral N17350 in Advanced Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07339176

Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06736379

Immunotherapy With Chemotherapy and Chemoradiation for Advanced Squamous Cancer of Nasal Cavity / Paranasal Sinuses (I-NAPA)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05027633

Effects of Infusion Timing on Treatment Response in Solid Tumors

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07630168

Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07513389

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

A Study of IDP-001 in Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07602842

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Sep 2, 2026 · NCT04915183

Toripalimab With Chemotherapy for Sinus Cancer

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT06940180

T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 2
Ages 18 to 72 · All sexes · Updated Aug 31, 2026 · NCT02133196

Machine Learning Analysis of Two-photon Fluorescence Microscopy of Dermatologic Biopsies

Recruiting
All ages · All sexes · Updated Aug 19, 2026 · NCT07682831

Two-photon Fluorescence Microscopy of Dermatologic Biopsies

Recruiting
All ages · All sexes · Updated Aug 19, 2026 · NCT07773688

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

Recruiting
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07241585

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT05859074

Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT02507141

Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06819228

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07628634

Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT05388773

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous SCC for Immunocompromised Patients

Recruiting
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06615635

PDT For Induction Therapy For Head And Neck Cancer

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07214987

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.