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Synovial Sarcoma clinical trials recruiting in the U.S.

13 studies for Synovial Sarcoma are recruiting participants at sites across the United States.

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Recently updated studies

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06644755

SPEARHEAD-3 Pediatric Study

RecruitingPhase 1/2
Ages 2 to 21 · All sexes · Updated Aug 11, 2026 · NCT05642455

Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1

RecruitingPhase 1
Ages 16 to 80 · All sexes · Updated Jul 29, 2026 · NCT06083883

AOH1996 for the Treatment of Refractory Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT05227326

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

RecruitingPhase 1/2
6 Months – 25 Years · All sexes · Updated Jun 30, 2026 · NCT06625190

Synovial Sarcoma Registry / Biospecimen Repository

RecruitingObservational study
All ages · All sexes · Updated Jun 9, 2026 · NCT05910307

Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT03016819

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

RecruitingPhase 1
Ages 1 to 25 · All sexes · Updated Jan 22, 2026 · NCT04995003

ACTengine® IMA203 Combined With mRNA-4203

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 8, 2026 · NCT06946225

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.