Home › Systolic Heart Failure
Systolic Heart Failure clinical trials recruiting in the U.S.
14 studies for Systolic Heart Failure are recruiting participants at sites across the United States.
Cities with the most studies
By state
Recently updated studies
A Study of LY3971297 in Participants With Heart Failure
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT07547540Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Neuromodulation of Inflammation and Endothelial Function
Recruiting
Ages 18 to 85 · All sexes · Updated Aug 11, 2026 · NCT05230732Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07467668Paced Heart Rate Acceleration for Cardiac Conditioning
Recruiting
Ages 18 to 120 · All sexes · Updated Jun 25, 2026 · NCT06332391A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
Recruiting
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT06671015The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Recruiting
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT05427370Developing a Digital Aid to Improve ICD Decisions
Recruiting
Ages 60 and older · All sexes · Updated Apr 27, 2026 · NCT07084142Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 24, 2026 · NCT07209098Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes
RecruitingEarly phase 1
Ages 18 to 80 · All sexes · Updated Jan 21, 2026 · NCT06108076Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 24, 2025 · NCT06009276Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 23, 2025 · NCT07131631Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Mar 26, 2024 · NCT04703842Mechanistic Clinical Trial of Advanced Imaging for CRT
Recruiting
Ages 20 to 90 · All sexes · Updated Feb 6, 2020 · NCT03398369From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.