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T-Cell Prolymphocytic Leukemia clinical trials recruiting in the U.S.
7 studies for T-Cell Prolymphocytic Leukemia are recruiting participants at sites across the United States.
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Recently updated studies
A Study of Ruxolitinib and Duvelisib in People With Lymphoma
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05010005Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07311746Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT06810778A Registry for People With T-cell Lymphoma
RecruitingObservational study
All ages · All sexes · Updated May 20, 2026 · NCT05978141Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
RecruitingPhase 1
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 15, 2026 · NCT07356245A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT04496349From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.