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Treatment-Resistant Depressive Disorder clinical trials in Florida

6 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Florida.

Cities in Florida

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

  • New Access Research and Medical Services, Inc., Fort Myers
  • The Medici Medical Research, Hollywood
  • Clinical Neuroscience Solutions, Inc., Orlando
  • and 2 more
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Nov 5, 2026 · NCT07284667

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

  • Mindful Behavioral Health, Boca Raton
  • Galiz Research LLC, Hialeah
  • Flourish Research - St. Augustine, Jacksonville
  • and 4 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT03887715

A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

  • American Family Research Group, Cape Coral
  • Pharmax Research Clinic Inc, Miami
  • Charter Research Orlando, Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07716098

ALTO-207 in Adults With Treatment-resistant Depression (TRD)

  • Site 7152, Saint Augustine
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 26, 2026 · NCT07553637

A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial

  • HOPE Study Site, Sarasota
  • HOPE Accelerated Care, West Palm Beach
RecruitingPhase 2/3
Ages 18 to 80 · All sexes · Updated Oct 21, 2026 · NCT07227103

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

  • USF Health, Tampa
Recruiting
Ages 22 to 70 · All sexes · Updated Oct 16, 2026 · NCT06423430

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.