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Treatment-Resistant Depressive Disorder clinical trials in Illinois
4 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Illinois.
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- Rush University Medical Center, Chicago
- AMR- Baber Research, Inc., Naperville
- Psychiatric Medicine Associates, LLC, Skokie
- and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT03887715A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression
- Psychiatric Medicine Associates LLC, Skokie
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07716098ALTO-207 in Adults With Treatment-resistant Depression (TRD)
- Site 7192, Naperville
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 26, 2026 · NCT07553637Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
- Rush University Medical Center, Chicago
- University of Chicago, Chicago
Recruiting
Ages 22 to 70 · All sexes · Updated Oct 16, 2026 · NCT06423430From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.