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Treatment-Resistant Depressive Disorder clinical trials in Maryland
6 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Maryland.
Cities in Maryland
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Sep 14, 2026 · NCT06511908Natural History of Depression, Bipolar Disorder and Suicide Risk
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Aug 14, 2026 · NCT06462196A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- Sheppard Pratt Health System, Inc., Baltimore
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
- Sheppard Pratt, Baltimore
- Sunstone Medical, PC, Rockville
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830ALTO-207 in Adults With Treatment-resistant Depression (TRD)
- Site 7151, Annapolis
- Site 7054, Pikesville
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Apr 28, 2026 · NCT07553637Long-term Observation of Participants With Mood Disorders
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Nov 28, 2025 · NCT04877977From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.