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Treatment-Resistant Depressive Disorder clinical trials in New York

11 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in New York.

Cities in New York

A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

  • Neurobehavioral Research Inc, Cedarhurst
  • The Medical Research Network, LLC, New York
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07716098

Biomarker-Guided Antidepressant Selection

  • Weill Cornell Medicine, New York
RecruitingPhase 4
Ages 18 to 70 · All sexes · Updated Sep 23, 2026 · NCT07680140

DBS for TRD With the Medtronic Percept PC

  • Icahn School of Medicine at Mount Sinai, Mount Sinai West, New York
Recruiting
Ages 25 to 70 · All sexes · Updated Sep 22, 2026 · NCT05773755

DBS for Depression

  • Zucker Hillside Hospital, Queens
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT06096207

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

  • Integrative Clinical Trials LLC, Brooklyn
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07284667

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

  • Mount Sinai Hospital, New York
Recruiting
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

  • Dent Neurological Institute, Amherst
  • Trinity Medical, Lewiston
  • Icahn School of Medicine at Mount Sinai, New York
  • and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

  • The Medical Research Network, LLC, New York
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

Maintenance rTMS for Depression (Maitr-De)

  • Weill Cornell Medicine, New York
Recruiting
Ages 18 to 80 · All sexes · Updated Apr 29, 2026 · NCT06938841

ALTO-207 in Adults With Treatment-resistant Depression (TRD)

  • Site 7170, Amherst
  • Site 7055, Cedarhurst
  • Site 7162, Lewiston
  • and 1 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Apr 28, 2026 · NCT07553637

Biomarker-guided rTMS for Treatment Resistant Depression

  • Weill Cornell Medicine, New York
RecruitingPhase 3
Ages 22 to 65 · All sexes · Updated Feb 25, 2026 · NCT04041479

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.