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Treatment-Resistant Depressive Disorder clinical trials in Ohio
5 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Ohio.
Cities in Ohio
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
- Neuro-Behavioral Clinical Research, North Canton
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Nov 5, 2026 · NCT07284667A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- The Ohio State University, Columbus
- Signature Research Associates, Inc., Fairlawn
- Charak Center for Health and Wellness, Garfield Heights
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT03887715A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression
- Ohio State University, Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07716098ALTO-207 in Adults With Treatment-resistant Depression (TRD)
- Site 7029, Cincinnati
- Site 7194, Dayton
- Site 7158, Garfield Heights
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 26, 2026 · NCT07553637Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
- The Cleveland Clinic Foundation, Cleveland
- The Ohio State University, Columbus
Recruiting
Ages 22 to 70 · All sexes · Updated Oct 16, 2026 · NCT06423430From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.