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Treatment-Resistant Depressive Disorder clinical trials in Texas

8 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Texas.

Cities in Texas

Regulated Stimulation for Optimized Network Activity and Therapeutic Equilibrium

  • UTHealth Houston, Houston
  • Brain Health Consultants and TMS Center, Houston
Recruiting
Ages 22 to 85 · All sexes · Updated Nov 9, 2026 · NCT07594483

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

  • Baylor College of Medicine, Houston
  • Olympus Clinical Research, LLC, Katy
  • Family Psychiatry of The Woodlands, The Woodlands
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Nov 5, 2026 · NCT07284667

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

  • UT Health Austin, Mulva Clinic for the Neurosciences, Austin
  • University of Texas Southwestern, Dallas
  • Texas Tech University Health Science Center, El Paso
  • and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT03887715

ALTO-207 in Adults With Treatment-resistant Depression (TRD)

  • Site 7199, Austin
  • Site 7190, Bryan
  • Site 7176, Dallas
  • and 6 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 26, 2026 · NCT07553637

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

  • University of Texas Austin Dell Medical School, Austin
  • University of Texas Southwestern Medical Center at Dallas, Dallas
  • CHI St. Luke's Health Baylor College of Medicine Med. Ctr, Houston
  • and 1 more
Recruiting
Ages 22 to 70 · All sexes · Updated Oct 16, 2026 · NCT06423430

Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression

  • Wells Medicine, Houston
  • Texas A&M (Houston Methodist Hospital Location), Houston
RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 45 · All sexes · Updated Sep 15, 2026 · NCT06480201

Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

  • UT Southwestern Medical Center, Dallas
Recruiting
Ages 21 to 70 · All sexes · Updated Jul 15, 2026 · NCT03952962

Psilocybin rTMS for Treatment Resistant Depression

  • Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600, Austin
RecruitingPhase 2
Ages 22 to 65 · All sexes · Updated Nov 26, 2025 · NCT06132178

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.