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Trigeminal Neuralgia clinical trials recruiting in the U.S.

5 studies for Trigeminal Neuralgia are recruiting participants at sites across the United States.

Trigeminal neuralgia (TN or tic douloureux) causes extreme, sudden burning or shock-like pain in the face. Learn about the causes and treatments.

Recently updated studies

The Will Erwin Headache Research Center - Cluster Headache Study

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT02910323

OnabotulinumtoxinA for Trigeminal Neuralgia

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT06216886

Trigeminal Evoked Responses to Improve Rhizotomy

RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 26, 2025 · NCT05738096

Trigeminal Neuralgia Electrophysiology

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT05269472

RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

RecruitingObservational study
All ages · All sexes · Updated Sep 19, 2024 · NCT01885299

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.