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Trigeminal Neuralgia clinical trials recruiting in the U.S.
6 studies for Trigeminal Neuralgia are recruiting participants at sites across the United States.
Trigeminal neuralgia (TN or tic douloureux) causes extreme, sudden burning or shock-like pain in the face. Learn about the causes and treatments.
Recently updated studies
Trigeminal Neuralgia Electrophysiology
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT05269472Trigeminal Evoked Responses to Improve Rhizotomy
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05738096Safety of Cultured Allogeneic Adult Umbilical Cordor Placental Derived Stem Cells Exosomes for Trigeminal Neuralgia
RecruitingPhase 1
All ages · All sexes · Updated Oct 20, 2026 · NCT05152368The Will Erwin Headache Research Center - Cluster Headache Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT02910323OnabotulinumtoxinA for Trigeminal Neuralgia
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT06216886RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
RecruitingObservational study
All ages · All sexes · Updated Sep 19, 2024 · NCT01885299From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.