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Trigeminal Neuralgia Electrophysiology

RecruitingObservational studyHealthy volunteers welcome

Trigeminal Evoked Responses to Improve Rhizotomy

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria (TGN):

* Adults of 18 years or older
* Scheduled to undergo percutaneous rhizotomy for facial pain

Exclusion Criteria (TGN):

* Facial pain of unclear origin (i.e. not clearly TGN pain)
* Rhizotomy procedure canceled

Inclusion Criteria (Healthy controls)

* Adults of 18 years or older

Exclusion Criteria (Healthy Controls)

* Diagnosis or history of facial pain such as TMD or TGN
* History of migraine
* History of any functional pain disorder: fibromyalgia, IBS, CRPS
* Recent chronic pain (within last month)
* Unwilling to participate for two hours in lab
* Current acute pain

About the study

The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia. The evoked responses will be measured at two locations before and after the clinical rhizotomy including: the standard contralateral scalp (EEG) and at the gasserian ganglion through an FDA-approved recording electrode.

What is being tested

Sponsor: University of Minnesota · Participants: 30 · Started: Apr 4, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05269472

Locations in the U.S.

MinnesotaUniversity of Minnesota, Minneapolis

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.