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Triple-Negative Breast Cancer clinical trials in Florida
45 studies for Triple-Negative Breast Cancer are looking for participants at sites in Florida.
Cities in Florida
- Tampa14 studies
- Orlando12 studies
- Miami10 studies
- Jacksonville9 studies
- Sarasota8 studies
- Plantation4 studies
- West Palm Beach3 studies
- St. Petersburg3 studies
Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
- UM Sylvester Comprehensive Cancer Center at Aventura, Aventura
- UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
- and 7 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03606967A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
- AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0007), Altamonte Springs
- Orlando Health Cancer Institute ( Site 0012), Orlando
- Florida Cancer Specialists - East ( Site 7000), West Palm Beach
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06841354A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
- AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0044), Altamonte Springs
- Florida Cancer Specialists - South ( Site 7004), Fort Myers
- Bioresearch Partner ( Site 0072), Hialeah
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06966700A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
- AdventHealth Celebration, Celebration
- Florida Clinical Trials Group, Plantation
- Florida Cancer Specialists, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07503808A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
- AdventHealth Cancer Institute, Orlando
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Nov 5, 2026 · NCT06586957A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
- SCRI Florida Cancer Specialists - Sarasota, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07029399Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
- AdventHealth Altamonte Springs ( Site 0125), Altamonte Springs
- Orlando Health Cancer Institute ( Site 0030), Orlando
- Cleveland Clinic Martin North Hospital ( Site 0114), Stuart
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06393374A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
- Florida Cancer Specialists - Lake Nona, Orlando
- Florida Cancer Specialists - Sarasota, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06150664Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
- Mayo Clinic Florida, Jacksonville
- Cancer Specialists of North Florida, Jacksonville
- Jupiter Medical Center, Jupiter
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05633654Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
- USOR Florida Cancer Specialists South, Fort Myers
- USOR Florida Cancer Specialists North, St. Petersburg
- USOR Florida Cancer Specialists East, West Palm Beach
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05579366Study of XB010 in Subjects With Solid Tumors
- Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06545331Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
- Mayo Clinic Jacksonville, Jacksonville
- Moffitt Cancer Center, Tampa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT04981119SMP-3124LP in Adults With Advanced Solid Tumors
- Advent Health, Celebration
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06526819Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400
- Florida Cancer Specialists- Sarasota Cattlemen /ID# 261569, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06084481First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer
- Florida Cancer Specialists, Sarasota
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06799065Phase 1 Study of CLR 125 in Triple Negative Breast Cancer
- Mayo Clinic Florida, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT07311993The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- University of Miami - Sylvester Comprehensive Cancer Center, Miami
- Advent Health, Orlando
- Florida Cancer Specialists South, Port Charlotte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750Study of AVZO-021 in Patients With Advanced Solid Tumors
- Avenzo Therapeutics Recruiting Site, Sarasota
- Avenzo Therapeutics Recruiting Site, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05867251Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
- Baptist MD Anderson Cancer Center, Jacksonville
Recruiting
Ages 30 and older · Women · Updated Sep 25, 2026 · NCT02945579Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer
- Morton Plant Hospital - Baycare Health System, Clearwater
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05528133A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
- University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
- Sylvester Comprehensive Cancer Center, Miami
- Sara Cannon Research Institute Lake Nona, Orlando
- Hematology - Oncology Associates of the Treasure Coast, Port Saint Lucie
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors
- Biogenix Molecular, LLC, Miami
- Advent Health Medical Group Radiation Oncology at Central Florida, Orlando
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117Study of Screening Brain MRIs in Stage IV Breast Cancer
- Morton Plant Mease- Baycare, Clearwater
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT05115474First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
- University of Miami, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06657222A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
- BAPTIST ALLIANCE - MCI (Data Collection Only), Miami
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05570253Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies
- Cleveland Clinic Florida, Weston
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07211178Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1/2
Ages 16 and older · All sexes · Updated Aug 20, 2026 · NCT05269381A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
- Local Institution - 0296, Pembroke Pines
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06926868DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs
- Miami Baptist Cancer Institute/, Miami
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06176261Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
- Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 1
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06562192A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
- Mayo Clinic - Jacksonville, Jacksonville
- Florida Cancer Specialists, Sarasota
- Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia
- University of Miami Health System, Coral Gables
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT05768932MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05076760A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
- Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04300556I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
- H. Lee Moffitt Cancer Center and Research Institute, Tampa
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
- Miami Cancer Institute at Baptist Health (Kendall), Miami
- Miami Cancer Institute at Baptist Health, Plantation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT04468061Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy
- Moffitt Cancer Center, Tampa
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT06435351Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease
- Baptist Alliance - McI, Miami
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT03808337DecipHER Trial - DC1 Tx for Early-Stage TNBC and ER Low Positive Breast Cancer
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05504707From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.