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Triple-Negative Breast Cancer clinical trials in Orlando, FL

12 studies for Triple-Negative Breast Cancer are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

RecruitingPhase 3
  • Orlando Health Cancer Institute ( Site 0012), Orlando
  • AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0007), Altamonte Springs · 9 mi away
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06841354

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0044), Altamonte Springs · 9 mi away
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06966700

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

RecruitingPhase 1
  • AdventHealth Celebration, Celebration · 17 mi away
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07503808

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • AdventHealth Cancer Institute, Orlando
Ages 19 and older · All sexes · Updated Nov 5, 2026 · NCT06586957

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

RecruitingPhase 3
  • Orlando Health Cancer Institute ( Site 0030), Orlando
  • AdventHealth Altamonte Springs ( Site 0125), Altamonte Springs · 9 mi away
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06393374

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

RecruitingPhase 1
  • Florida Cancer Specialists - Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06150664

Study of XB010 in Subjects With Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06545331

SMP-3124LP in Adults With Advanced Solid Tumors

RecruitingPhase 1/2
  • Advent Health, Celebration · 17 mi away
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06526819

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Advent Health, Orlando
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Sara Cannon Research Institute Lake Nona, Orlando
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

RecruitingPhase 1
  • Advent Health Medical Group Radiation Oncology at Central Florida, Orlando
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

RecruitingPhase 1
  • Dren Investigational Site, Orlando
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187

Triple-Negative Breast Cancer trials in other cities

Other studies in Orlando

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.