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Type 1 Diabetes clinical trials recruiting in the U.S.

138 studies for Type 1 Diabetes are recruiting participants at sites across the United States.

If the pancreas doesn't make needed insulin, causing blood sugar levels to be too high you have type 1 or juvenile diabetes. Learn the signs.

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Recently updated studies

Starting Technology in At Risk Type 1 Diabetes Study

Recruiting
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06453928

ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2

Recruiting
Ages 8 to 21 · All sexes · Updated Sep 23, 2026 · NCT05463289

A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity

RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Sep 23, 2026 · NCT07803744

App-Based Certified Diabetes Education Therapy (AB-CDE)

Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07282639

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

RecruitingPhase 3
Ages 1 to 35 · All sexes · Updated Sep 22, 2026 · NCT07222137

Type 1 Diabetes Extension Study

RecruitingObservational study
Ages 8 to 35 · All sexes · Updated Sep 18, 2026 · NCT02734277

METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)

RecruitingPhase 2
Ages 18 to 69 · All sexes · Updated Sep 15, 2026 · NCT07699380

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

RecruitingPhase 1/2
Ages 12 to 35 · All sexes · Updated Sep 11, 2026 · NCT06783309

Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG

RecruitingPhase 2
Ages 4 to 34 · All sexes · Updated Sep 9, 2026 · NCT07216391

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

RecruitingPhase 2
Ages 8 to 45 · All sexes · Updated Sep 8, 2026 · NCT07142252

C-Carbs: A CGM-guided Approach to Teaching Carb Awareness

Recruiting
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07807280

The iLet Experience Study

RecruitingObservational study
Ages 6 and older · All sexes · Updated Sep 8, 2026 · NCT06891898

A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes

RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 1, 2026 · NCT04786262

Remedy to Diabetes Distress (R2D2): A Scalable Screen to Treat Program for School-age Families

Recruiting
Ages 8 to 65 · All sexes · Updated Sep 1, 2026 · NCT05268250

Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes

Recruiting
Ages 18 to 80 · All sexes · Updated Aug 28, 2026 · NCT07599982

HLA Demographics Study in Adults With Type 1 Diabetes

RecruitingObservational study
Ages 18 to 55 · All sexes · Updated Aug 28, 2026 · NCT06860516

Advancing Precision Nutrition: Wearable Technology for Noninvasive Insulin Monitoring

RecruitingHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Aug 28, 2026 · NCT07254364

Pilot Implementation Trial of Implementation Toolkits for Diabetes Coaching

RecruitingHealthy volunteers welcome
All ages · All sexes · Updated Aug 27, 2026 · NCT07766811

Family Intervention for Black Teens With Type 1 Diabetes

Recruiting
Ages 10 to 14 · All sexes · Updated Aug 27, 2026 · NCT06275412

Long-Term Outcomes of Teplizumab in Routine Clinical Care

RecruitingObservational study
All ages · All sexes · Updated Aug 25, 2026 · NCT07360080

SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes

RecruitingPhase 2
Ages 5 to 40 · All sexes · Updated Aug 24, 2026 · NCT07187531

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.