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Esophageal Adenocarcinoma clinical trials in New York City, NY

18 studies for Esophageal Adenocarcinoma are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

RecruitingPhase 2/3
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06203600

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

RecruitingPhase 3
  • Manhattan Eye Ear and Throat Hospital, New York
  • NYP/Weill Cornell Medical Center, New York
  • Lenox Hill Hospital, New York
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05677490

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

RecruitingPhase 1/2
  • Memorial Sloan-Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06324357

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

RecruitingPhase 2/3
  • Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York
  • Rockefeller Outpatient Pavilion (53rd Street), New York
  • Memorial Sloan Kettering Cancer Center - Main Campus, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07392892

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas

RecruitingPhase 2
  • Weill Cornell Medicine - New York Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07546812

A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction Adenocarcinoma

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activites), New York
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07818018

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

Recruiting
  • Columbia Universtiy, New York
Ages 18 to 89 · All sexes · Updated Sep 11, 2026 · NCT05753748

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

RecruitingPhase 3
  • Research Site, New York
  • Research Site, New York
  • Research Site, New York
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07431281

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • NYU Langone Health, New York
  • Icahn School of Medicine At Mount Sinai Prime, New York
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists, New York
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance

Recruiting
  • Weill Cornell Medicine, New York
Ages 18 to 89 · All sexes · Updated Jul 1, 2026 · NCT05530343

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Research Site, New York
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07284186

Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma

RecruitingPhase 2
  • Weill Cornell Medicine/NewYork-Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06340711

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • NYU Langone, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04900818

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Feb 11, 2026 · NCT06623396

Esophageal Adenocarcinoma trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.