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Head and Neck Squamous Cell Carcinoma clinical trials in Colorado

23 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in Colorado.

Cities in Colorado

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

  • UCHealth Memorial Hospital Central, Colorado Springs
  • Memorial Hospital North, Colorado Springs
  • Kaiser Permanente-Franklin, Denver
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06992427

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

  • Site #0122, Aurora
  • Site #0124, Aurora
  • Site#0121, Aurora
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • Sarah Cannon Research Institute at HealthOne, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #87, Littleton
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

  • UCHealth Memorial Hospital Central, Colorado Springs
  • Memorial Hospital North, Colorado Springs
  • Poudre Valley Hospital, Fort Collins
  • and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06589804

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

  • UCHealth Memorial Hospital Central, Colorado Springs
  • Memorial Hospital North, Colorado Springs
  • Poudre Valley Hospital, Fort Collins
  • and 3 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

  • University of Colorado Denver Anschultz Medical Campus, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06385080

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

  • University of Colorado Cancer Center, Aurora
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

  • Penrose-Saint Francis Healthcare, Colorado Springs
  • Rocky Mountain Cancer Centers-Penrose, Colorado Springs
  • Saint Francis Cancer Center, Colorado Springs
  • and 6 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • University of Colorado, Aurora
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

  • Normunity Investigational Site, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07182149

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

  • Shaw Cancer Center, Edwards
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

SMP-3124LP in Adults With Advanced Solid Tumors

  • Sarah Cannon Research Institute at HealthOne, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06526819

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

  • Rocky Mountain Cancer Centers, Lone Tree
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

  • University of Colorado Cancer Center, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

  • Sarah Cannon Research Institute at HealthONE, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

  • USA01-0, Wheat Ridge
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

Losartan, Pembrolizumab and Stereotactic Body Radiation Therapy for the Treatment of Patients With Locally Recurrent, Refractory or Oligometastatic Head and Neck Squamous Cell Carcinoma

  • University of Colorado Denver | Anschutz Medical Campus, Aurora
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT06211335

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

  • Sarah Cannon Research Institute at HealthONE, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

  • Dren Investigational Site, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

  • University of Colorado Cancer Center, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT05902988

A Study of NX-1607 in Adults With Advanced Malignancies

  • University of Colorado School of Medicine, Aurora
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT05107674

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

  • Sarah Cannon Research Institute at HealthONE, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 15, 2024 · NCT04787042

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.