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Lung Cancer clinical trials in Charlotte, NC

7 studies for Lung Cancer are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Novant Health Presbyterian Medical Center, Charlotte
  • Novant Health Cancer Institute - Matthews, Matthews · 10 mi away
  • Novant Health Cancer Institute - Huntersville, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04181060

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

RecruitingPhase 3
  • Carolinas Medical Center, Charlotte
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06765109

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

RecruitingPhase 1/2
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06287775

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
  • Atrium Health Pineville/LCI-Pineville, Charlotte
  • and 11 more
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Charlotte
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

RecruitingHealthy volunteers welcome
  • Levine Cancer Institute, Charlotte
Ages 40 to 54 · All sexes · Updated Jul 13, 2026 · NCT04577599

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.